GAB1 and LAT2

  • Data Source:
  • HPRD (in vitro, in vivo)

GAB1

LAT2

Description GRB2 associated binding protein 1 linker for activation of T cells family member 2
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Asthma ( 21804548)
  • Diastolic blood pressure ( 27841878)
  • Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858)
  • Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858)
  • Estimated glomerular filtration rate in non-diabetics ( 31451708)
  • Height ( 31562340)
  • Malaria ( 31844061)
  • Systolic blood pressure ( 27841878)
  • Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858)
  • Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858)
  • Systemic lupus erythematosus ( 29848360)
Interacting Genes 73 interacting genes: ARHGAP32 BCAR3 BLK BLNK BTK C1QBP CRK CRKL EGFR EPOR ERBB2 FCGR2B FES FRS2 GAB2 GRAP2 GRB2 GTF2A1L HCK HSH2D INPP5D INPPL1 INSR ITK JAK1 LAT2 LCK LYN MAP3K3 MAPK1 MAPK3 MAPK4 MARK2 MET MST1R NCK1 NCK2 PDGFRB PIK3CG PIK3R1 PIK3R2 PIK3R3 PLCG1 PLCG2 PTK6 PTPN11 PTPN18 RASA1 RET SH2D1B SH2D2A SH2D3A SHC1 SHC3 SLA SLA2 SOCS3 SOCS6 SOS1 SRC STAP1 SUPT6H SYK SYP TEC TNS1 TNS3 TNS4 TRIM15 VAV1 VAV2 VAV3 YES1 7 interacting genes: CBL GAB1 GRB2 PLCG1 PLCG2 SOS1 UBQLN4
Entrez ID 2549 7462
HPRD ID 05116 09304
Ensembl ID ENSG00000109458 ENSG00000086730
Uniprot IDs Q13480 Q9HA84 Q9GZY6
PDB IDs 4QSY 3MAZ
Enriched GO Terms of Interacting Partners?
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