RABGAP1 and MAP1LC3A

Data Source:
BioGRID (pull down)

		RABGAP1	MAP1LC3A
Description		RAB GTPase activating protein 1	microtubule associated protein 1 light chain 3 alpha
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GO Annotations	Cellular Component	Centrosome Cytosol Microtubule Associated Complex	Autophagosome Membrane Late Endosome Autophagosome Cytosol Microtubule Organelle Membrane Intracellular Membrane-bounded Organelle Autolysosome Synapse
	Molecular Function	GTPase Activator Activity Protein Binding Tubulin Binding Small GTPase Binding	Protein Binding Phospholipid Binding Microtubule Binding Phosphatidylethanolamine Binding Ubiquitin Protein Ligase Binding
	Biological Process	Intracellular Protein Transport Cell Cycle Regulation Of GTPase Activity Activation Of GTPase Activity Regulation Of Cilium Assembly	Autophagosome Assembly Autophagy Of Mitochondrion Cellular Response To Nitrogen Starvation Cellular Response To Starvation Response To Iron(II) Ion Response To Lead Ion Macroautophagy Cellular Response To Amino Acid Starvation Response To Morphine Cellular Response To Hydrogen Peroxide Cellular Response To Copper Ion Autophagosome Maturation
Pathways		TBC/RABGAPs	Macroautophagy PINK1-PRKN Mediated Mitophagy Receptor Mediated Mitophagy
Drugs
Diseases
GWAS		Birth weight ( 31043758) Body mass index ( 26426971) Brain morphology (MOSTest) ( 32665545) HDL cholesterol levels x thiazide or thiazide-like diuretics use interaction ( 31806883) Pulse pressure ( 27841878 30578418) Systolic blood pressure ( 27841878)	Bipolar disorder ( 31043756) Colorectal cancer or advanced adenoma ( 30510241) Fish- and plant-related diet ( 32066663) Oily fish consumption ( 32066663) Pork consumption ( 32066663)
Interacting Genes		10 interacting genes: CARM1 DISC1 GABARAPL1 MAP1LC3A RAB4A RAB6A RAB6B SENP1 SENP5 STAT3	54 interacting genes: AKAP13 AMBRA1 ANK2 ANK3 APP ATG13 ATG4B ATG7 ATXN3 BNIP3L DVL2 EPHA7 FUNDC1 GPSM1 IRGQ KIF15 KXD1 LMNB1 MAP1A MAP1S MDM2 MEFV MREG NBR1 NEDD4 OPRM1 OPTN PIAS4 PRPF40A RABGAP1 RABGAP1L RDH12 RETREG3 RTKN SQSTM1 SRPK1 TBC1D1 TBC1D10A TBC1D10B TBC1D16 TBC1D17 TBC1D2 TBC1D25 TBC1D2B TBC1D5 TBC1D7 TBC1D9 TBC1D9B TNIP1 TP53INP1 TRIM21 TRIM32 TUBA4A VPS9D1
Entrez ID		23637	84557
HPRD ID		06575	03144
Ensembl ID		ENSG00000011454	ENSG00000101460
Uniprot IDs		Q9Y3P9	Q9H492
PDB IDs		4NC6	3ECI 3WAL 3WAN 4ZDV 5CX3 5DPR
Enriched GO Terms of Interacting Partners?
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