MAP1LC3A and ATG4B

Data Source:
BioGRID (two hybrid, enzymatic study)

		MAP1LC3A	ATG4B
Description		microtubule associated protein 1 light chain 3 alpha	autophagy related 4B cysteine peptidase
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GO Annotations	Cellular Component	Autophagosome Membrane Late Endosome Autophagosome Cytosol Microtubule Organelle Membrane Intracellular Membrane-bounded Organelle Autolysosome Synapse	Cytosol
	Molecular Function	Protein Binding Phospholipid Binding Microtubule Binding Phosphatidylethanolamine Binding Ubiquitin Protein Ligase Binding	Endopeptidase Activity Cysteine-type Endopeptidase Activity Protein Binding Cysteine-type Peptidase Activity
	Biological Process	Autophagosome Assembly Autophagy Of Mitochondrion Cellular Response To Nitrogen Starvation Cellular Response To Starvation Response To Iron(II) Ion Response To Lead Ion Macroautophagy Cellular Response To Amino Acid Starvation Response To Morphine Cellular Response To Hydrogen Peroxide Cellular Response To Copper Ion Autophagosome Maturation	Proteolysis Autophagy Protein Transport Macroautophagy Positive Regulation Of Protein Catabolic Process Protein Delipidation
Pathways		Macroautophagy PINK1-PRKN Mediated Mitophagy Receptor Mediated Mitophagy	Macroautophagy
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756) Colorectal cancer or advanced adenoma ( 30510241) Fish- and plant-related diet ( 32066663) Oily fish consumption ( 32066663) Pork consumption ( 32066663)	Asthma ( 31959851) Body mass index ( 29273807) Carotid intima media thickness ( 30510157) Crohn's disease ( 26192919) Prostate cancer ( 23535732)
Interacting Genes		54 interacting genes: AKAP13 AMBRA1 ANK2 ANK3 APP ATG13 ATG4B ATG7 ATXN3 BNIP3L DVL2 EPHA7 FUNDC1 GPSM1 IRGQ KIF15 KXD1 LMNB1 MAP1A MAP1S MDM2 MEFV MREG NBR1 NEDD4 OPRM1 OPTN PIAS4 PRPF40A RABGAP1 RABGAP1L RDH12 RETREG3 RTKN SQSTM1 SRPK1 TBC1D1 TBC1D10A TBC1D10B TBC1D16 TBC1D17 TBC1D2 TBC1D25 TBC1D2B TBC1D5 TBC1D7 TBC1D9 TBC1D9B TNIP1 TP53INP1 TRIM21 TRIM32 TUBA4A VPS9D1	6 interacting genes: GABARAP GABARAPL1 GABARAPL2 MAP1LC3A MAP1LC3B MAP1LC3C
Entrez ID		84557	23192
HPRD ID		03144	16499
Ensembl ID		ENSG00000101460	ENSG00000168397
Uniprot IDs		Q9H492	B3KVU2 Q9Y4P1
PDB IDs		3ECI 3WAL 3WAN 4ZDV 5CX3 5DPR	2CY7 2D1I 2Z0D 2Z0E 2ZZP 5LXH 5LXI
Enriched GO Terms of Interacting Partners?
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