MAP1LC3A and ATG7

Data Source:
BioGRID (pull down)

		MAP1LC3A	ATG7
Description		microtubule associated protein 1 light chain 3 alpha	autophagy related 7
Image			No pdb structure
GO Annotations	Cellular Component	Autophagosome Membrane Late Endosome Autophagosome Cytosol Microtubule Organelle Membrane Intracellular Membrane-bounded Organelle Autolysosome Synapse	Phagophore Assembly Site Extracellular Region Cytoplasm Cytosol Axoneme Axon Secretory Granule Lumen Ficolin-1-rich Granule Lumen
	Molecular Function	Protein Binding Phospholipid Binding Microtubule Binding Phosphatidylethanolamine Binding Ubiquitin Protein Ligase Binding	Protein Binding Transcription Factor Binding Atg12 Activating Enzyme Activity Atg8 Activating Enzyme Activity Protein Homodimerization Activity
	Biological Process	Autophagosome Assembly Autophagy Of Mitochondrion Cellular Response To Nitrogen Starvation Cellular Response To Starvation Response To Iron(II) Ion Response To Lead Ion Macroautophagy Cellular Response To Amino Acid Starvation Response To Morphine Cellular Response To Hydrogen Peroxide Cellular Response To Copper Ion Autophagosome Maturation	Autophagosome Assembly Autophagy Of Mitochondrion Protein Lipidation C-terminal Protein Lipidation Autophagy Cellular Response To Nitrogen Starvation Aging Cellular Response To Starvation Response To Glucose Protein Transport Macroautophagy Protein Phosphopantetheinylation Positive Regulation Of Protein Modification Process Protein Modification By Small Protein Conjugation Piecemeal Microautophagy Of The Nucleus Suppression By Virus Of Host Autophagy Regulation Of Circadian Rhythm Positive Regulation Of Apoptotic Process Neutrophil Degranulation Late Nucleophagy Positive Regulation Of Protein Catabolic Process Rhythmic Process Defense Response To Virus Chaperone-mediated Autophagy Cellular Response To Morphine Cellular Response To Hyperoxia Positive Regulation By Symbiont Of Host Autophagy Negative Regulation Of Mitochondrial DNA Replication Response To Fluoride Negative Regulation Of Oxidative Stress-induced Neuron Death
Pathways		Macroautophagy PINK1-PRKN Mediated Mitophagy Receptor Mediated Mitophagy	Macroautophagy Macroautophagy Neutrophil degranulation Signaling by BRAF and RAF fusions Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756) Colorectal cancer or advanced adenoma ( 30510241) Fish- and plant-related diet ( 32066663) Oily fish consumption ( 32066663) Pork consumption ( 32066663)	Body fat mass ( 28552196) Body size at age 10 ( 32376654) Circulating chemerin levels ( 25521368) HDL cholesterol ( 24097068 25961943) HDL cholesterol levels ( 28334899) Heel bone mineral density ( 28869591) Male-pattern baldness ( 28196072) Pulse pressure ( 30578418) Relative hand skill in reading disability ( 24068947) Small vessel stroke ( 29123153) Systolic blood pressure ( 27618447 27618452 30578418)
Interacting Genes		54 interacting genes: AKAP13 AMBRA1 ANK2 ANK3 APP ATG13 ATG4B ATG7 ATXN3 BNIP3L DVL2 EPHA7 FUNDC1 GPSM1 IRGQ KIF15 KXD1 LMNB1 MAP1A MAP1S MDM2 MEFV MREG NBR1 NEDD4 OPRM1 OPTN PIAS4 PRPF40A RABGAP1 RABGAP1L RDH12 RETREG3 RTKN SQSTM1 SRPK1 TBC1D1 TBC1D10A TBC1D10B TBC1D16 TBC1D17 TBC1D2 TBC1D25 TBC1D2B TBC1D5 TBC1D7 TBC1D9 TBC1D9B TNIP1 TP53INP1 TRIM21 TRIM32 TUBA4A VPS9D1	10 interacting genes: APP ATG10 ATG12 ATG3 EEF1D GABARAP GABARAPL2 IRF2 MAP1LC3A MAP1LC3B
Entrez ID		84557	10533
HPRD ID		03144	12293
Ensembl ID		ENSG00000101460	ENSG00000197548
Uniprot IDs		Q9H492	B3KQM6 O95352
PDB IDs		3ECI 3WAL 3WAN 4ZDV 5CX3 5DPR
Enriched GO Terms of Interacting Partners?
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