RABGAP1 and RAB6B

Data Source:
HPRD (two hybrid)

		RABGAP1	RAB6B
Description		RAB GTPase activating protein 1	RAB6B, member RAS oncogene family
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GO Annotations	Cellular Component	Centrosome Cytosol Microtubule Associated Complex	Golgi Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Cytosol Endomembrane System Cytoplasmic Vesicle Presynapse
	Molecular Function	GTPase Activator Activity Protein Binding Tubulin Binding Small GTPase Binding	GTPase Activity Protein Binding GTP Binding Myosin V Binding
	Biological Process	Intracellular Protein Transport Cell Cycle Regulation Of GTPase Activity Activation Of GTPase Activity Regulation Of Cilium Assembly	Intracellular Protein Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Intra-Golgi Vesicle-mediated Transport Retrograde Transport, Endosome To Golgi
Pathways		TBC/RABGAPs	COPI-independent Golgi-to-ER retrograde traffic Retrograde transport at the Trans-Golgi-Network TBC/RABGAPs RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases
GWAS		Birth weight ( 31043758) Body mass index ( 26426971) Brain morphology (MOSTest) ( 32665545) HDL cholesterol levels x thiazide or thiazide-like diuretics use interaction ( 31806883) Pulse pressure ( 27841878 30578418) Systolic blood pressure ( 27841878)	Blood protein levels ( 30072576) Immune reponse to smallpox (secreted IL-1beta) ( 22610502) Iron status biomarkers (total iron binding capacity) ( 28334935) Mean corpuscular hemoglobin ( 32888494) Mean reticulocyte volume ( 32888494) Post bronchodilator FEV1/FVC ratio ( 26634245)
Interacting Genes		10 interacting genes: CARM1 DISC1 GABARAPL1 MAP1LC3A RAB4A RAB6A RAB6B SENP1 SENP5 STAT3	14 interacting genes: ACVR1 BICD2 BMPR1B COG6 ERC1 KIF20A LNX2 MEOX2 PMM1 RABGAP1 RAP1GDS1 SH2B2 SMAD1 TGFBR1
Entrez ID		23637	51560
HPRD ID		06575	11474
Ensembl ID		ENSG00000011454	ENSG00000154917
Uniprot IDs		Q9Y3P9	Q9NRW1
PDB IDs		4NC6	2E9S 2FE4 2FFQ
Enriched GO Terms of Interacting Partners?
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