EMP3 and TSPAN12

Data Source:
BioGRID (two hybrid)

		EMP3	TSPAN12
Description		epithelial membrane protein 3	tetraspanin 12
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane	Integral Component Of Plasma Membrane Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding	Protein Binding Wnt-activated Receptor Activity
	Biological Process	Cell Death Bleb Assembly	Angiogenesis Cell Surface Receptor Signaling Pathway Retina Layer Formation Wnt Signaling Pathway Regulation Of Angiogenesis Regulation Of Vascular Endothelial Growth Factor Signaling Pathway
Pathways
Drugs
Diseases			Familial exudative vitreoretinopathy (FEVR), including: Exudative vitreoretinopathy 1 (EVR1); Exudative vitreoretinopathy2, X-linked (EVR2); Exudative vitreoretinopathy 4 (EVR4); Exudative vitreoretinopathy 5 (EVR5); Norrie disease (ND)
GWAS			Bitter alcoholic beverage consumption ( 31046077) Heel bone mineral density ( 30598549)
Interacting Genes		43 interacting genes: AQP6 CD79A CLDN2 CLDN7 CREB3L1 CREM EDA ELOVL7 ERGIC3 FAM210B FNDC9 GJA5 GJB1 GPA33 GPR61 IFNGR2 IL3RA KIR3DL3 KLRC1 LDLRAD1 LEUTX LHFPL5 LRRC4C LYVE1 MR1 MS4A3 MUC1 OPRM1 P2RX7 PLEKHB2 RMDN3 SAR1A SECTM1 SIGLECL1 SLAMF8 SLC30A2 SLC35C2 SMIM3 SPACA1 TM4SF18 TMX2 TSPAN12 VSIG1	21 interacting genes: CDS2 CTXN3 CXCL16 CYBC1 EMP3 GPR25 GPR37L1 IGFBP5 MARCHF2 MGST3 NINJ2 PMP22 RFT1 RNF152 STX8 TEX264 TFCP2 TMEM140 TMEM147 TMEM182 TMEM218
Entrez ID		2014	23554
HPRD ID		18514	15509
Ensembl ID		ENSG00000142227	ENSG00000106025
Uniprot IDs		A0A024QZF8 P54852	A0A024R740 O95859
PDB IDs
Enriched GO Terms of Interacting Partners?
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