TSPAN12 and GPR25

Data Source:
BioGRID (two hybrid)

		TSPAN12	GPR25
Description		tetraspanin 12	G protein-coupled receptor 25
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Integral Component Of Plasma Membrane Membrane Integral Component Of Membrane	Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	Protein Binding Wnt-activated Receptor Activity	G Protein-coupled Receptor Activity Protein Binding
	Biological Process	Angiogenesis Cell Surface Receptor Signaling Pathway Retina Layer Formation Wnt Signaling Pathway Regulation Of Angiogenesis Regulation Of Vascular Endothelial Growth Factor Signaling Pathway	G Protein-coupled Receptor Signaling Pathway
Pathways			G alpha (s) signalling events ADORA2B mediated anti-inflammatory cytokines production
Drugs
Diseases		Familial exudative vitreoretinopathy (FEVR), including: Exudative vitreoretinopathy 1 (EVR1); Exudative vitreoretinopathy2, X-linked (EVR2); Exudative vitreoretinopathy 4 (EVR4); Exudative vitreoretinopathy 5 (EVR5); Norrie disease (ND)
GWAS		Bitter alcoholic beverage consumption ( 31046077) Heel bone mineral density ( 30598549)	Ankylosing spondylitis ( 23749187) Autoimmune thyroid disease ( 32581359) Refractive error ( 32231278)
Interacting Genes		21 interacting genes: CDS2 CTXN3 CXCL16 CYBC1 EMP3 GPR25 GPR37L1 IGFBP5 MARCHF2 MGST3 NINJ2 PMP22 RFT1 RNF152 STX8 TEX264 TFCP2 TMEM140 TMEM147 TMEM182 TMEM218	32 interacting genes: AQP6 ATP6V0C ATP6V0E1 BEST2 CNIH4 CREB3L1 CREB3L3 FATE1 GGT7 GJB1 IKBIP KASH5 LDLRAD1 LMNA MAP3K7 MFSD5 MMGT1 NAALADL2 PNMA1 RETN RHCG SHISAL1 SLC16A7 SLC35E3 SLCO4A1 STOM TMEM237 TMEM248 TMEM52B TPRA1 TSPAN12 VAPB
Entrez ID		23554	2848
HPRD ID		15509	03707
Ensembl ID		ENSG00000106025	ENSG00000170128
Uniprot IDs		A0A024R740 O95859	O00155
PDB IDs
Enriched GO Terms of Interacting Partners?
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