EMP3 and MR1

Data Source:
BioGRID (two hybrid)

		EMP3	MR1
Description		epithelial membrane protein 3	major histocompatibility complex, class I-related
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane	Golgi Membrane Extracellular Space Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane External Side Of Plasma Membrane Integral Component Of Membrane Early Endosome Membrane Late Endosome Membrane MHC Class I Protein Complex
	Molecular Function	Protein Binding	Protein Binding Beta-2-microglobulin Binding MHC Class I Receptor Activity T Cell Receptor Binding
	Biological Process	Cell Death Bleb Assembly	Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Positive Regulation Of T Cell Mediated Cytotoxicity Directed Against Tumor Cell Target Immune Response Antigen Processing And Presentation Of Exogenous Antigen T Cell Differentiation In Thymus Innate Immune Response Defense Response To Gram-negative Bacterium Defense Response To Gram-positive Bacterium
Pathways
Drugs			Antithymocyte immunoglobulin (rabbit)
Diseases
GWAS			Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Post bronchodilator FEV1 ( 26634245) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		43 interacting genes: AQP6 CD79A CLDN2 CLDN7 CREB3L1 CREM EDA ELOVL7 ERGIC3 FAM210B FNDC9 GJA5 GJB1 GPA33 GPR61 IFNGR2 IL3RA KIR3DL3 KLRC1 LDLRAD1 LEUTX LHFPL5 LRRC4C LYVE1 MR1 MS4A3 MUC1 OPRM1 P2RX7 PLEKHB2 RMDN3 SAR1A SECTM1 SIGLECL1 SLAMF8 SLC30A2 SLC35C2 SMIM3 SPACA1 TM4SF18 TMX2 TSPAN12 VSIG1	7 interacting genes: CDS2 CXCL9 EMP3 ERMP1 FATE1 GALNT15 NINJ2
Entrez ID		2014	3140
HPRD ID		18514	09012
Ensembl ID		ENSG00000142227	ENSG00000153029
Uniprot IDs		A0A024QZF8 P54852	Q95460
PDB IDs			4GUP 4L4T 4L4V 4LCW 4NQC 4NQD 4NQE 4PJ5 4PJ7 4PJ8 4PJ9 4PJA 4PJB 4PJC 4PJD 4PJE 4PJF 4PJG 4PJH 4PJI 4PJX 5D5M 5D7I 5D7J 5D7L 5U16 5U17 5U1R 5U2V 5U6Q 5U72 6MWR 6PUC 6PUD 6PUE 6PUF 6PUG 6PUH 6PUI 6PUJ 6PUK 6PUL 6PUM 6PVC 6PVD 6W9U 6W9V 6XQP
Enriched GO Terms of Interacting Partners?
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