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TSPAN12 and CXCL16
Data Source:
BioGRID
(two hybrid)
TSPAN12
CXCL16
Description
tetraspanin 12
C-X-C motif chemokine ligand 16
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Integral Component Of Plasma Membrane
Membrane
Integral Component Of Membrane
Extracellular Region
Extracellular Space
Plasma Membrane
Membrane
Integral Component Of Membrane
Molecular Function
Protein Binding
Wnt-activated Receptor Activity
Low-density Lipoprotein Particle Receptor Activity
Scavenger Receptor Activity
Chemokine Activity
Biological Process
Angiogenesis
Cell Surface Receptor Signaling Pathway
Retina Layer Formation
Wnt Signaling Pathway
Regulation Of Angiogenesis
Regulation Of Vascular Endothelial Growth Factor Signaling Pathway
Receptor-mediated Endocytosis
Chemotaxis
G Protein-coupled Receptor Signaling Pathway
T Cell Chemotaxis
Positive Regulation Of Cell Growth
Positive Regulation Of Cell Migration
Response To Cytokine
Response To Interferon-gamma
Response To Tumor Necrosis Factor
Pathways
Chemokine receptors bind chemokines
G alpha (i) signalling events
Drugs
Diseases
Familial exudative vitreoretinopathy (FEVR), including: Exudative vitreoretinopathy 1 (EVR1); Exudative vitreoretinopathy2, X-linked (EVR2); Exudative vitreoretinopathy 4 (EVR4); Exudative vitreoretinopathy 5 (EVR5); Norrie disease (ND)
GWAS
Bitter alcoholic beverage consumption (
31046077
)
Heel bone mineral density (
30598549
)
Blood protein levels (
30072576
29875488
)
Blood protein levels in cardiovascular risk (
28369058
)
Interacting Genes
21 interacting genes:
CDS2
CTXN3
CXCL16
CYBC1
EMP3
GPR25
GPR37L1
IGFBP5
MARCHF2
MGST3
NINJ2
PMP22
RFT1
RNF152
STX8
TEX264
TFCP2
TMEM140
TMEM147
TMEM182
TMEM218
63 interacting genes:
ADAMTSL4
APP
AQP2
AQP6
AQP9
ARL13B
ATP6V0E1
BIK
CARD10
CCDC70
CD53
CERS4
CLDN7
CREB3L1
CXCR6
CYSRT1
FAM209A
FFAR2
FKBP7
FNDC9
GJA8
GORAB
GPR42
HHATL
HOXA1
KASH5
KIR2DL3
KRT31
KRTAP1-3
KRTAP10-1
KRTAP10-3
KRTAP10-7
KRTAP10-9
KRTAP17-1
KRTAP2-3
KRTAP2-4
KRTAP5-9
LHFPL5
LMNA
MDFI
MFF
MTUS2
MUC1
NBPF19
NEMP1
NOTCH2NLA
PEX12
SAR1A
SLC16A2
SLC18A1
SLC39A1
SPN
SSMEM1
STX1A
TGM1
TLCD4
TMEM139
TMEM14B
TMEM237
TMEM239
TMEM35A
TMX2
TSPAN12
Entrez ID
23554
58191
HPRD ID
15509
16103
Ensembl ID
ENSG00000106025
ENSG00000161921
Uniprot IDs
A0A024R740
O95859
A0A6I8PIU0
Q9H2A7
PDB IDs
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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