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PHC2 and C1orf109
Data Source:
BioGRID
(two hybrid)
PHC2
C1orf109
Description
polyhomeotic homolog 2
chromosome 1 open reading frame 109
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Heterochromatin
Nucleus
Nucleoplasm
PcG Protein Complex
PRC1 Complex
Nucleus
Nucleoplasm
Nucleolus
Cytoplasm
Cytosol
Molecular Function
DNA Binding
Chromatin Binding
Protein Binding
Zinc Ion Binding
Histone Binding
Identical Protein Binding
Protein Binding
Biological Process
Multicellular Organism Development
Spermatogenesis
Negative Regulation Of Transcription, DNA-templated
Pathways
Oxidative Stress Induced Senescence
SUMOylation of DNA damage response and repair proteins
SUMOylation of transcription cofactors
SUMOylation of chromatin organization proteins
SUMOylation of RNA binding proteins
SUMOylation of DNA methylation proteins
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
Regulation of PTEN gene transcription
Regulation of PTEN gene transcription
Drugs
Diseases
GWAS
Adventurousness (
30643258
)
Blood urea nitrogen levels (
31152163
29403010
)
General risk tolerance (MTAG) (
30643258
)
Pulse pressure (
30224653
)
Risk-taking tendency (4-domain principal component model) (
30643258
)
Smoking status (ever vs never smokers) (
30643258
)
Urinary albumin excretion (
30220432
)
Urinary albumin-to-creatinine ratio (
31630189
)
Axial length (
24144296
)
Eyebrow thickness (
26926045
)
Interacting Genes
79 interacting genes:
AEN
AFG3L2
AP1M1
BMI1
BSDC1
BYSL
C1orf109
CARD9
CBX2
CRK
CRKL
CSNK2B
DRG1
ENKD1
FAM124A
FAM13C
FAM161A
FAM74A1
FAM74A4
FHL3
FOSB
GFI1B
GRB2
H3-4
HDAC7
KAT5
KBTBD7
KDM1A
KIFC3
KLHDC7B
KRT31
L3MBTL3
LMO1
LMO2
LMO3
MAB21L3
MAGEB6
MAPK14
MAPK6
MAPKAPK2
MCM2
MCRS1
MFAP1
MLLT6
MORF4L2
NCK1
PCGF2
PCGF3
PCGF5
PHC1
PLAGL2
PLK1
POLR2L
PPP1R16B
PRKAA1
PRPF3
PRPF31
RBM39
RNF2
RPL7
RWDD2B
SCMH1
SDCBP
SFMBT1
SIAH1
SMAD3
SPATC1L
SSX2IP
SYT16
TAB1
THAP7
TMEM70
TRIM41
TRIM55
TRIM63
ZBTB24
ZGPAT
ZMAT2
ZNF417
144 interacting genes:
ABI2
ADD1
ANTKMT
ATP23
AVPI1
BORCS6
C1orf94
C1QTNF2
C9orf24
CBY2
CCDC120
CCDC125
CCDC33
CCDC88B
CCHCR1
CDCA4
CEP55
CINP
CRX
CSNK2A1
CT55
CTAG1A
CTAG1B
DISC1
ECM1
ECSIT
FAM217B
FAM86C1P
FTO
GET4
GIGYF1
GOLGA2
GOLGA6A
GOLGA6L9
HESX1
HOOK2
HOXC8
IHO1
IKZF1
IKZF3
INKA1
KATNAL1
KIAA0753
KIFC3
KLF15
KRT13
KRT16
KRT18
KRT19
KRT24
KRT31
KRT35
KRT40
KRT75
KRT76
KRT80
KRTAP13-3
LDOC1
LMO2
LZTS2
MBD3L1
MDM4
MEI4
MEOX1
MEOX2
MIPOL1
MKRN2
MTFR1L
MTUS2
NDUFB7
NECAB2
NFKBID
NME4
NUP54
NUTM2F
OOEP
PAX5
PAX6
PAX7
PBX4
PDE4DIP
PHC2
PLK4
PNMA1
POMC
POU6F2
PPP1R12C
PRDM6
PRMT5
PSMB4
PUDP
REL
RINT1
RNF20
RNF41
RPH3AL
RUSC1
SAPCD2
SDCBP
SERTAD1
SERTAD2
SLAIN1
SMARCD1
SOCS6
SORBS3
SPAG5
STMN3
STN1
STX11
TADA2A
TASOR2
TCF12
TCF4
TEKT4
TEPSIN
TFIP11
TLE5
TNNI2
TRAF1
TRIM27
TRIM42
TRIM54
TSGA10IP
TTC12
TTC23
TTC23L
UHMK1
USH1G
USHBP1
VBP1
VGLL1
VPS52
YPEL3
ZBED1
ZBTB42
ZMAT1
ZMAT5
ZMYND12
ZNF17
ZNF20
ZNF398
ZNF420
ZNF688
ZSCAN9
Entrez ID
1912
54955
HPRD ID
10340
07918
Ensembl ID
ENSG00000134686
ENSG00000116922
Uniprot IDs
A0A0A0MSI2
Q8IXK0
B4DRQ5
B7Z9X8
Q9NX04
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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