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TXLNB and AXIN2
Data Source:
BioGRID
(two hybrid)
TXLNB
AXIN2
Description
taxilin beta
axin 2
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Cytoplasm
Nucleus
Cytoplasm
Centrosome
Cytosol
Beta-catenin Destruction Complex
Molecular Function
Protein Binding
Syntaxin Binding
Protein Binding
Beta-catenin Binding
Enzyme Binding
Ubiquitin Protein Ligase Binding
I-SMAD Binding
Biological Process
Somitogenesis
Positive Regulation Of Protein Phosphorylation
Intramembranous Ossification
Secondary Heart Field Specification
Chondrocyte Differentiation Involved In Endochondral Bone Morphogenesis
Cell Population Proliferation
Negative Regulation Of Cell Population Proliferation
Positive Regulation Of Epithelial To Mesenchymal Transition
Positive Regulation Of Cell Death
Wnt Signaling Pathway
Bone Mineralization
Regulation Of Mismatch Repair
Cellular Protein Localization
Odontogenesis
Maintenance Of DNA Repeat Elements
Negative Regulation Of Osteoblast Differentiation
MRNA Stabilization
Regulation Of Chondrocyte Development
Regulation Of Centromeric Sister Chromatid Cohesion
Negative Regulation Of Canonical Wnt Signaling Pathway
Positive Regulation Of Canonical Wnt Signaling Pathway
Beta-catenin-TCF Complex Assembly
Pathways
TCF dependent signaling in response to WNT
Binding of TCF/LEF:CTNNB1 to target gene promoters
Degradation of AXIN
Ub-specific processing proteases
Drugs
Diseases
Tooth agenesis; Hypodontia
Oligodontia-colorectal cancer syndrome
GWAS
Albumin-globulin ratio (
29403010
)
Caudate volume in trauma-exposed individuals (
29187748
)
Heel bone mineral density (
30598549
)
Non-albumin protein levels (
29403010
)
Waist-to-hip ratio adjusted for BMI (
26426971
)
Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) (
26426971
)
Blond vs. brown/black hair color (
30531825
)
Heel bone mineral density (
30598549
28869591
)
Height (
31562340
)
Refractive error (
32231278
)
Interacting Genes
70 interacting genes:
AXIN2
BTF3
BTF3L4
C18orf54
CAGE1
CBY2
CCDC13
CCDC14
CCDC152
CCDC196
CCDC88B
CCHCR1
CDR2
CEP19
CEP57
CEP57L1
CEP63
CEP70
CFAP53
CT55
DCTN2
DEUP1
DMAP1
DYDC1
EXOC5
FAM161A
FAM167A
GAS8
GOLGA2
HAUS3
KIAA1328
KRT13
KRT15
KRT16
KRT26
KRT27
KRT34
KRT35
KRT37
KRT38
KRT39
KRT6A
KRT75
LPXN
LURAP1
LZTS1
MBIP
MED4
MEOX2
MNS1
NEFL
NF2
NMI
ODAD3
SIKE1
SNAPC5
SOX13
STMN3
STX1A
STX4
TADA3
TCL1A
TXLNA
UBE2I
USHBP1
UTP14A
VIM
VPS52
WASHC3
ZNF20
52 interacting genes:
AMOT
ANKRD6
AP1M1
APC
APC2
BARD1
BTRC
BYSL
C2orf68
CAPN7
CCDC112
CHIC2
CSNK1E
CTAG2
CTNNB1
CWF19L2
ELOA
FAM161A
FBP1
FBP2
GSK3B
HEMGN
HOXB5
KCNK12
KIFC3
KRTAP10-10
KRTAP10-8
KRTAP4-5
KRTAP9-2
LNX1
MCRS1
PPP2R5A
PRDX1
PSMB2
RANGAP1
SCNM1
SMAD1
SMAD3
SMAD7
STX11
TCEA2
TCEANC
TGFB1
TOP3B
TSGA10
TXLNA
TXLNB
ZNF124
ZNF189
ZNF417
ZNF587
ZNF648
Entrez ID
167838
8313
HPRD ID
10793
04935
Ensembl ID
ENSG00000164440
ENSG00000168646
Uniprot IDs
H0UI60
Q8N3L3
E7ES00
Q9Y2T1
PDB IDs
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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