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TXLNB and NF2
Data Source:
BioGRID
(two hybrid)
TXLNB
NF2
Description
taxilin beta
neurofibromin 2
Image
No pdb structure
GO Annotations
Cellular Component
Cytoplasm
Nucleus
Nucleolus
Cytoplasm
Early Endosome
Cytosol
Cytoskeleton
Plasma Membrane
Adherens Junction
Membrane
Lamellipodium
Cortical Actin Cytoskeleton
Filopodium Membrane
Cleavage Furrow
Ruffle Membrane
Neuron Projection
Cell Body
Apical Part Of Cell
Perinuclear Region Of Cytoplasm
Molecular Function
Protein Binding
Syntaxin Binding
Actin Binding
Protein Binding
Biological Process
Mesoderm Formation
Negative Regulation Of Cell-matrix Adhesion
Negative Regulation Of Protein Kinase Activity
Ectoderm Development
Negative Regulation Of Cell Population Proliferation
Schwann Cell Proliferation
Regulation Of Gliogenesis
Hippocampus Development
Negative Regulation Of Cell-cell Adhesion
Actin Cytoskeleton Organization
Negative Regulation Of Cell Migration
Regulation Of Protein Stability
Regulation Of Hippo Signaling
Odontogenesis Of Dentin-containing Tooth
Negative Regulation Of Tyrosine Phosphorylation Of STAT Protein
Regulation Of Apoptotic Process
Negative Regulation Of MAPK Cascade
Cell-cell Junction Organization
Positive Regulation Of Cell Differentiation
Negative Regulation Of Receptor Signaling Pathway Via JAK-STAT
Positive Regulation Of Stress Fiber Assembly
Regulation Of Cell Cycle
Lens Fiber Cell Differentiation
Regulation Of Stem Cell Proliferation
Regulation Of Protein Localization To Nucleus
Regulation Of Neural Precursor Cell Proliferation
Pathways
Regulation of actin dynamics for phagocytic cup formation
RHO GTPases activate PAKs
Drugs
Diseases
Malignant pleural mesothelioma
Noonan syndrome and related disorders, including: Noonan syndrome (NS); Leopard syndrome (LS); Noonan syndrome-like with loose anagen hair (NS/LAH); CBL-mutation associated syndrome (CBL); Neurofibromatosis type 1 (NF1); Neurofibromatosis type 2 (NF2); Neurofibromatosis-Noonan syndrome (NFNS); Legius syndrome; Cardiofaciocutaneous syndrome (CFCS); Costello syndrome (CS)
GWAS
Albumin-globulin ratio (
29403010
)
Caudate volume in trauma-exposed individuals (
29187748
)
Heel bone mineral density (
30598549
)
Non-albumin protein levels (
29403010
)
Waist-to-hip ratio adjusted for BMI (
26426971
)
Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) (
26426971
)
Carotid atherosclerosis in HIV infection (
20009918
)
Interacting Genes
70 interacting genes:
AXIN2
BTF3
BTF3L4
C18orf54
CAGE1
CBY2
CCDC13
CCDC14
CCDC152
CCDC196
CCDC88B
CCHCR1
CDR2
CEP19
CEP57
CEP57L1
CEP63
CEP70
CFAP53
CT55
DCTN2
DEUP1
DMAP1
DYDC1
EXOC5
FAM161A
FAM167A
GAS8
GOLGA2
HAUS3
KIAA1328
KRT13
KRT15
KRT16
KRT26
KRT27
KRT34
KRT35
KRT37
KRT38
KRT39
KRT6A
KRT75
LPXN
LURAP1
LZTS1
MBIP
MED4
MEOX2
MNS1
NEFL
NF2
NMI
ODAD3
SIKE1
SNAPC5
SOX13
STMN3
STX1A
STX4
TADA3
TCL1A
TXLNA
UBE2I
USHBP1
UTP14A
VIM
VPS52
WASHC3
ZNF20
74 interacting genes:
AGAP2
AKT1
AMOT
AMOTL2
ARAF
ARNT
AURKA
BDKRB1
BECN1
BYSL
CBLC
CCNB1IP1
CCND2
CCNE1
CD44
CDK4
CDK6
CDKN2B
CDKN2C
CTNNB1
DACH1
DCAF1
EGFR
EIF3B
EMD
EPHA2
ERBB2
EZR
FGFR4
FZR1
GLIS2
GRM1
HGF
HGS
HIF1A
IGF1R
ITGB1
KAT2A
KDELR2
KDM1A
LATS1
LATS2
MAP2K3
MAP2K5
MAP3K5
MAPK14
MDM4
MED28
MET
MYBPC2
MYC
PAK1
PDGFRA
PRKCA
PXN
PYGO2
RAF1
RALGDS
RASSF1
SCHIP1
SDCBP
SGSM3
SLC9A3R1
SOX3
SOX4
SPTBN1
STK11
TARBP2
TERT
TP53
TSC1
TTYH2
TXLNB
XPO1
Entrez ID
167838
4771
HPRD ID
10793
06980
Ensembl ID
ENSG00000164440
ENSG00000186575
Uniprot IDs
H0UI60
Q8N3L3
A0A024R1D9
A0A024R1F6
A0A024R1I0
A0A024R1J8
A0A024R1J9
P35240
PDB IDs
1H4R
3U8Z
4ZRI
4ZRJ
6CDS
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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