SMCR8 and TBK1

  • Data Source:
  • BioGRID (enzymatic study)

SMCR8

TBK1

Description SMCR8-C9orf72 complex subunit TANK binding kinase 1
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Change in neurofilament light levels ( 31295725)
  • Diastolic blood pressure ( 30578418)
  • Systolic blood pressure ( 30578418)
  • Amyotrophic lateral sclerosis ( 29566793 27455348)
  • High light scatter reticulocyte count ( 32888494)
  • High light scatter reticulocyte percentage of red cells ( 32888494)
  • Lung adenocarcinoma ( 28604730)
  • Reticulocyte count ( 32888494)
  • Reticulocyte fraction of red cells ( 32888494)
Interacting Genes 4 interacting genes: ATG13 C9orf72 TBK1 ULK1 44 interacting genes: AGO2 APP ATG9A AZI2 CALCOCO2 CDC37 CDC42BPG CYLD HSP90AA1 HSP90AB1 IKBKB IKBKG IRF3 IRF5 IRF7 MAP1LC3B MAVS MBP MIB2 MTPAP NCK1 NEDD4 NFKBIA PROS1 PTPRD RELA RIPK1 RNF128 RPS6KB1 SIKE1 SMCR8 SMURF1 SQSTM1 STX11 TANK TICAM1 TRAF2 TRAF3 TRAF3IP2 TRAF5 TRIM21 TRIM27 TXLNG XIAP
Entrez ID 140775 29110
HPRD ID 18075 05322
Ensembl ID ENSG00000176994 ENSG00000183735
Uniprot IDs Q8TEV9 Q9UHD2
PDB IDs 6LT0 6V4U 4EFO 4EUT 4EUU 4IM0 4IM2 4IM3 4IW0 4IWO 4IWP 4IWQ 5EOA 5EOF 5EP6 5W5V 6BNY 6BOD 6BOE 6CQ0 6CQ4 6CQ5 6NT9 6O8B 6RSR 6RST 6RSU
Enriched GO Terms of Interacting Partners?
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