SMCR8

Description		SMCR8-C9orf72 complex subunit
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GO Annotations	Cellular Component	Chromatin Nucleoplasm Cytoplasm Guanyl-nucleotide Exchange Factor Complex Atg1/ULK1 Kinase Complex
	Molecular Function	Protein Kinase Inhibitor Activity Guanyl-nucleotide Exchange Factor Activity Protein Binding Protein Kinase Binding
	Biological Process	Negative Regulation Of Protein Kinase Activity Autophagy Regulation Of Autophagy Negative Regulation Of Gene Expression Negative Regulation Of Macroautophagy Positive Regulation Of TOR Signaling Positive Regulation Of Autophagosome Maturation Negative Regulation Of Autophagosome Assembly Regulation Of TORC1 Signaling
Pathways
Drugs
Diseases
GWAS		Change in neurofilament light levels ( 31295725) Diastolic blood pressure ( 30578418) Systolic blood pressure ( 30578418)
Novel Interacting Genes		2 novel interacting genes: DRC3 TOM1L2
Interacting Genes		4 interacting genes: ATG13 C9orf72 TBK1 ULK1
Entrez ID		140775
HPRD ID		18075
Ensembl ID		ENSG00000176994
Uniprot IDs		Q8TEV9
PDB IDs		6LT0 6V4U
Enriched GO Terms of Interacting Partners?
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