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FAM168B and GLIS2
Data Source:
BioGRID
(two hybrid)
FAM168B
GLIS2
Description
family with sequence similarity 168 member B
GLIS family zinc finger 2
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Plasma Membrane
Integral Component Of Membrane
Axon
Perinuclear Region Of Cytoplasm
Extracellular Exosome
Nucleus
Nucleoplasm
Cytoplasm
Nuclear Speck
Non-motile Cilium
Molecular Function
Transcription Regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
Protein Binding
Metal Ion Binding
Sequence-specific Double-stranded DNA Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Regulation Of Transcription By RNA Polymerase II
Central Nervous System Development
Negative Regulation Of DNA-binding Transcription Factor Activity
Negative Regulation Of Smoothened Signaling Pathway
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription By RNA Polymerase II
Regulation Of Transcription From RNA Polymerase II Promoter Involved In Kidney Development
Cell Differentiation Involved In Kidney Development
Hematopoietic Stem Cell Homeostasis
Positive Regulation Of Protein Localization To Nucleus
Pathways
Drugs
Diseases
Nephronophthisis-medullary cystic kidney disease, including; Nephronophthisis (NPH) ; Nephronophthisis-like nephropathy 1; Medullary cystic kidney disease 1; Medullary cystic kidney disease 2 (MSKD2)
GWAS
Erectile dysfunction (
30583798
)
Heel bone mineral density (
30598549
)
Lung function (FEV1/FVC) (
26635082
)
Prostate-specific antigen levels (
28139693
)
Interacting Genes
51 interacting genes:
AGXT
ARID5A
BAG3
CAMK2A
CCNK
CSTF2
CSTF2T
EGLN3
FAM168A
FAM222B
FOXH1
FOXI1
GLIS2
GPS2
HOXB9
HSF4
KRTAP26-1
LASP1
MED25
MSRB3
MYOZ3
NEDD9
OTX1
PATZ1
PITX1
POGZ
POM121
PPP1R32
PRR35
RAMAC
RBFOX2
RHOXF2
ROR2
SAMD7
SNRPB
SNRPC
SPAG8
TCF7L2
TENT5B
TIAL1
TLE5
TLX3
UBAP2
VENTX
VEZF1
VGLL3
VPS37C
WDR25
YPEL3
ZC3H10
ZIC1
92 interacting genes:
ACTN3
AKAP9
AKT1
ANKRD36B
ARAF
ARID5A
ARNT
BCAR1
BECN1
C19orf54
CBLC
CCND2
CCNE1
CD44
CDK4
CDK6
CDKN2A
CDKN2B
CPSF1
CREM
CRX
CSNK2B
CTBP2
CTNNB1
EPHA2
ERBB2
FAM168B
FGFR4
FOSB
FZR1
GLIS1
GMNN
GOLGA6L9
GPSM1
GPSM2
HGF
HIF1A
KRTAP19-3
KRTAP19-5
KRTAP19-7
KRTAP6-1
KRTAP6-2
KRTAP8-1
LATS2
MAP2K3
MAP2K5
MAP2K6
MAP3K5
MDM2
MDM4
MET
MYC
NF2
NFIC
NME7
NSD3
OIP5
PIK3CA
PLEKHB1
PLEKHB2
POU6F2
PRKAR1B
PRR20A
PRR20B
PRR20C
PRR20D
PRR20E
RAF1
RASSF1
RBFOX2
RBM11
RBPMS
SHOX
SOX3
SPECC1L
STK11
TEAD2
TENT5A
TERT
TLE5
TRIM32
TSC1
TWIST2
U2AF2
VAC14
VBP1
VENTX
WNK1
WT1
WWOX
XAB2
ZRANB1
Entrez ID
130074
84662
HPRD ID
17295
12256
Ensembl ID
ENSG00000152102
ENSG00000126603
Uniprot IDs
A0A024QZ31
A1KXE4
B3KTH4
Q9BZE0
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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