GLIS2 and GOLGA6L9

Data Source:
BioGRID (two hybrid)

		GLIS2	GOLGA6L9
Description		GLIS family zinc finger 2	golgin A6 family like 9
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Nuclear Speck Non-motile Cilium
	Molecular Function	Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding	Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Central Nervous System Development Negative Regulation Of DNA-binding Transcription Factor Activity Negative Regulation Of Smoothened Signaling Pathway Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription From RNA Polymerase II Promoter Involved In Kidney Development Cell Differentiation Involved In Kidney Development Hematopoietic Stem Cell Homeostasis Positive Regulation Of Protein Localization To Nucleus
Pathways
Drugs
Diseases		Nephronophthisis-medullary cystic kidney disease, including; Nephronophthisis (NPH) ; Nephronophthisis-like nephropathy 1; Medullary cystic kidney disease 1; Medullary cystic kidney disease 2 (MSKD2)
GWAS		Erectile dysfunction ( 30583798) Heel bone mineral density ( 30598549) Lung function (FEV1/FVC) ( 26635082) Prostate-specific antigen levels ( 28139693)	Tourette syndrome ( 30818990)
Interacting Genes		92 interacting genes: ACTN3 AKAP9 AKT1 ANKRD36B ARAF ARID5A ARNT BCAR1 BECN1 C19orf54 CBLC CCND2 CCNE1 CD44 CDK4 CDK6 CDKN2A CDKN2B CPSF1 CREM CRX CSNK2B CTBP2 CTNNB1 EPHA2 ERBB2 FAM168B FGFR4 FOSB FZR1 GLIS1 GMNN GOLGA6L9 GPSM1 GPSM2 HGF HIF1A KRTAP19-3 KRTAP19-5 KRTAP19-7 KRTAP6-1 KRTAP6-2 KRTAP8-1 LATS2 MAP2K3 MAP2K5 MAP2K6 MAP3K5 MDM2 MDM4 MET MYC NF2 NFIC NME7 NSD3 OIP5 PIK3CA PLEKHB1 PLEKHB2 POU6F2 PRKAR1B PRR20A PRR20B PRR20C PRR20D PRR20E RAF1 RASSF1 RBFOX2 RBM11 RBPMS SHOX SOX3 SPECC1L STK11 TEAD2 TENT5A TERT TLE5 TRIM32 TSC1 TWIST2 U2AF2 VAC14 VBP1 VENTX WNK1 WT1 WWOX XAB2 ZRANB1	215 interacting genes: ANKRD11 ARHGAP9 ASXL1 ATP6V1G1 ATPAF2 ATXN7L2 AVPI1 BAG6 BAHD1 BANP BCL6B BHLHA9 BYSL C1orf109 C1orf35 C22orf15 C3 CABP2 CATIP CAVIN3 CBX8 CCDC116 CCDC120 CCDC146 CCDC185 CCDC187 CCHCR1 CDC37 CDC73 CDK18 CEP72 CEP95 CNNM3 CWF19L2 DAXX DEF6 DENND5A DES DOCK2 DPF2 DUSP26 EAF1 EIF3D ENKD1 FAAP20 FAM107A FAM110A FAM161A FAM161B FAM207A FBXO28 FEM1A FLYWCH1 FXN GADD45GIP1 GAS2L2 GEM GLIS2 GPANK1 GTF2B HAPLN2 HBZ HDAC4 HDAC7 HGS HOXB5 HOXB9 HOXC8 IL16 INO80B ISCU JMY JRK KANK2 KCTD9 KLHL35 KRT1 KRT75 LAGE3 LENG1 LGALS4 LMO3 LMO4 LYSMD1 M1AP MAB21L2 MBD3 MBD3L2 MFAP1 MOS MRPL11 MYOZ3 NAB2 NDUFAF3 NSMF NTAQ1 NXF1 NXT2 ORC1 PATZ1 PCDHB14 PHF1 PIN1 PKN1 PNMA5 POLL POLR1C POU6F2 PPP1R18 PRKAB2 PRPF18 PRPF31 PWWP2B RANBP3L RASSF10 RIN1 RLN1 RNF39 RNPS1 RTP5 SCAND1 SCNM1 SH2D4A SHC3 SLIRP SMARCD1 SMARCE1 SNAI1 SSX5 STAMBPL1 STK25 SUOX SUV39H1 SUV39H2 TACO1 TBC1D30 TCEANC TEAD4 THAP7 TJAP1 TLE5 TLX3 TMSB4X TPRX1 TRAF3IP3 TRAF4 TRIM14 TSEN54 TSFM TSGA10IP TSPYL4 TTC23 TXN2 TYK2 UBASH3A UBL4B UBTFL1 USHBP1 USP2 VEZF1 WDR25 ZBTB16 ZBTB24 ZFHX3 ZFP1 ZGPAT ZKSCAN3 ZMAT2 ZNF124 ZNF155 ZNF165 ZNF17 ZNF20 ZNF205 ZNF230 ZNF250 ZNF264 ZNF32 ZNF329 ZNF35 ZNF410 ZNF414 ZNF417 ZNF438 ZNF444 ZNF446 ZNF479 ZNF48 ZNF490 ZNF497 ZNF524 ZNF552 ZNF557 ZNF574 ZNF578 ZNF580 ZNF581 ZNF587 ZNF599 ZNF624 ZNF628 ZNF629 ZNF648 ZNF669 ZNF696 ZNF764 ZNF785 ZNF792 ZNF80 ZNF835 ZNF837 ZNF844 ZNHIT1 ZSCAN23 ZSCAN26
Entrez ID		84662	440295
HPRD ID		12256
Ensembl ID		ENSG00000126603	ENSG00000197978
Uniprot IDs		B3KTH4 Q9BZE0	A6NEM1
PDB IDs
Enriched GO Terms of Interacting Partners?
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