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AP2M1 and ZNF581
Data Source:
BioGRID
(two hybrid)
AP2M1
ZNF581
Description
adaptor related protein complex 2 subunit mu 1
zinc finger protein 581
Image
No pdb structure
GO Annotations
Cellular Component
Lysosomal Membrane
Cytosol
Plasma Membrane
Clathrin-coated Pit
AP-2 Adaptor Complex
Endocytic Vesicle Membrane
Clathrin-coated Endocytic Vesicle Membrane
Cytoplasmic Vesicle
Endolysosome Membrane
Intracellular Membrane-bounded Organelle
Clathrin-coated Endocytic Vesicle
Extracellular Exosome
Nucleus
Molecular Function
Signal Sequence Binding
Protein Binding
Lipid Binding
Clathrin Adaptor Activity
Ion Channel Binding
Low-density Lipoprotein Particle Receptor Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity
Protein Binding
Metal Ion Binding
Biological Process
Intracellular Protein Transport
Endocytosis
Vesicle Budding From Membrane
Vesicle-mediated Transport
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II
Receptor Internalization
Low-density Lipoprotein Particle Receptor Catabolic Process
Low-density Lipoprotein Particle Clearance
Cellular Protein-containing Complex Assembly
Ephrin Receptor Signaling Pathway
Regulation Of Defense Response To Virus By Virus
Wnt Signaling Pathway, Planar Cell Polarity Pathway
Membrane Organization
Clathrin-dependent Endocytosis
Regulation Of Vesicle Size
Negative Regulation Of Protein Localization To Plasma Membrane
Regulation Of Transcription By RNA Polymerase II
Pathways
Nef mediated downregulation of CD28 cell surface expression
Nef Mediated CD4 Down-regulation
Retrograde neurotrophin signalling
Retrograde neurotrophin signalling
Nef Mediated CD8 Down-regulation
Gap junction degradation
Formation of annular gap junctions
MHC class II antigen presentation
EPH-ephrin mediated repulsion of cells
Recycling pathway of L1
Recycling pathway of L1
WNT5A-dependent internalization of FZD4
WNT5A-dependent internalization of FZD2, FZD5 and ROR2
Cargo recognition for clathrin-mediated endocytosis
Clathrin-mediated endocytosis
VLDLR internalisation and degradation
LDL clearance
Potential therapeutics for SARS
Drugs
Diseases
GWAS
Major depressive disorder (
22472876
)
Interacting Genes
76 interacting genes:
ADRA1B
AGTR1
AP2B1
AQP4
ARRB2
ATXN1L
BDKRB2
C1orf35
CACNA1A
CD22
CD3D
CDK11B
CORO7
CSNK2B
CTLA4
CXorf51A
CXorf51B
DAB2
DCX
DPPA2
DVL2
EAF1
EHD2
EIF1AD
FAM90A1
FURIN
FXR2
GAK
GRIN2B
H2BC10
H2BC13
H2BC21
H2BC4
H2BC6
H2BC7
H2BC8
HEXIM2
HTR6
IKZF1
KCNJ11
KNOP1
LAMP1
LTB4R2
LY9
MAB21L3
MED4
MEGF10
MFAP1
MPP1
MTURN
NAA11
NCOR2
NDRG1
NKAPD1
PRPF18
PRPF38A
PRR13
PTS
RALBP1
RNF111
RPL22
RPL38
RRP12
RSPH14
RUNDC3A
SFRP4
STON2
SYNJ1
TASOR
TBC1D5
TGOLN2
TMA16
UBC
UTP25
ZBTB8A
ZNF581
95 interacting genes:
AP2M1
APOBEC3C
APP
ASB13
ATG9A
BANP
BOLA2
BOLA2B
CALCOCO2
CARD10
CBY2
CCDC136
CCNDBP1
CHURC1
CNFN
CYSRT1
DAZAP2
DOCK8
DVL2
DVL3
EFEMP2
ENKD1
ETFDH
FAM90A1
FANCL
FHL5
FSD2
GOLGA2
GOLGA6L9
GOPC
GPSM3
HMBOX1
HNRNPC
HNRNPF
HSF2BP
IKZF1
IL16
KDM1A
KHDRBS2
KRT27
KRT34
KRT40
KRTAP1-1
KRTAP10-1
KRTAP10-3
KRTAP10-7
KRTAP10-8
KRTAP10-9
KRTAP12-2
KRTAP2-3
KRTAP2-4
KRTAP4-12
KRTAP4-2
KRTAP5-9
KRTAP6-2
LNX1
LNX2
LZTS2
MDFI
MGAT5B
MTUS2
NBPF19
NID2
NOTCH2NLA
NUDT22
PDE4DIP
PLAGL2
PLEKHF2
PLSCR1
PNMA1
POU2AF1
PRKAB2
RBPMS
RIMBP3C
RSKR
SDCBP2
SERTAD2
SMARCC1
SOX5
SPAG8
SPG21
SUV39H1
TEKT4
TMCC2
TRAF1
TRAF4
TRIM23
TRIM27
TRIM55
TRIM63
TRIP6
WWOX
ZNF765
ZNF792
ZRANB1
Entrez ID
1173
51545
HPRD ID
03014
15858
Ensembl ID
ENSG00000161203
ENSG00000171425
Uniprot IDs
B4DNB9
E9PFW3
Q96CW1
Q9P0T4
PDB IDs
1H6E
6BNT
6URI
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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