ZWINT and BFSP1

Data Source:
BioGRID (two hybrid)

		ZWINT	BFSP1
Description		ZW10 interacting kinetochore protein	beaded filament structural protein 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Kinetochore Condensed Chromosome Kinetochore Nucleoplasm Cytoplasm Cytosol Nuclear Body Dendrite	Cytoplasm Intermediate Filament Plasma Membrane Cell Cortex
	Molecular Function	Protein Binding Protein N-terminus Binding	Structural Constituent Of Cytoskeleton Structural Constituent Of Eye Lens Protein Binding
	Biological Process	Mitotic Sister Chromatid Segregation Mitotic Cell Cycle Checkpoint Mitotic Spindle Assembly Checkpoint Cell Division Establishment Of Localization In Cell	Biological_process Intermediate Filament Organization Cell Maturation Lens Fiber Cell Development
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS		Cardiac hypertrophy ( 21348951) Erosive tooth wear (severe vs non-severe) ( 29898447) Erosive tooth wear (severe vs none or mild) ( 29898447) Liver fibrosis (total hepatic collagen content) ( 32953199)	Estimated glomerular filtration rate after 1 year in renal transplantation (donor effect) ( 30920136) Waist circumference adjusted for body mass index ( 28552196)
Interacting Genes		17 interacting genes: APP BCAS2 BFSP1 CCHCR1 CLU DSN1 FAM90A1 KRT75 LIG4 MAFB MIS12 MSGN1 NDC80 NUP54 PHAX TSG101 ZW10	12 interacting genes: BFSP2 BYSL CCHCR1 EMILIN1 KIFC3 KRT27 LINC00839 NUP62 SNAPIN USHBP1 VIM ZWINT
Entrez ID		11130	631
HPRD ID		18366	04494
Ensembl ID		ENSG00000122952	ENSG00000125864
Uniprot IDs		O95229	B7Z999 B7ZAD2 Q12934
PDB IDs
Enriched GO Terms of Interacting Partners?
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