BFSP1 and EMILIN1

Data Source:
BioGRID (two hybrid)

		BFSP1	EMILIN1
Description		beaded filament structural protein 1	elastin microfibril interfacer 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Intermediate Filament Plasma Membrane Cell Cortex	Extracellular Region Collagen Trimer Extracellular Space Integrin Alpha4-beta1 Complex Collagen-containing Extracellular Matrix Extracellular Exosome EMILIN Complex
	Molecular Function	Structural Constituent Of Cytoskeleton Structural Constituent Of Eye Lens Protein Binding	Extracellular Matrix Structural Constituent Protein Binding Extracellular Matrix Constituent Conferring Elasticity Identical Protein Binding Integrin Binding Involved In Cell-matrix Adhesion
	Biological Process	Biological_process Intermediate Filament Organization Cell Maturation Lens Fiber Cell Development	Aortic Valve Morphogenesis Cell Adhesion Cell-matrix Adhesion Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Positive Regulation Of Cell-substrate Adhesion Cell Migration Negative Regulation Of Angiogenesis Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Negative Regulation Of Collagen Biosynthetic Process Elastic Fiber Assembly Negative Regulation Of Cell Activation Negative Regulation Of Pathway-restricted SMAD Protein Phosphorylation Negative Regulation Of ERK1 And ERK2 Cascade Positive Regulation Of Extracellular Matrix Assembly Negative Regulation Of Collagen Fibril Organization Negative Regulation Of Macrophage Migration
Pathways			Molecules associated with elastic fibres Molecules associated with elastic fibres
Drugs
Diseases
GWAS		Estimated glomerular filtration rate after 1 year in renal transplantation (donor effect) ( 30920136) Waist circumference adjusted for body mass index ( 28552196)	Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		12 interacting genes: BFSP2 BYSL CCHCR1 EMILIN1 KIFC3 KRT27 LINC00839 NUP62 SNAPIN USHBP1 VIM ZWINT	29 interacting genes: ABI3 BEX3 BEX5 BFSP1 CDCA8 CENPQ COG7 DYNC1I1 EMILIN2 FBXO28 GNG13 IFT20 LAIR2 LRRIQ1 MIA2 MTMR9 NECAB2 NMI PLAC9 PRKAA2 RABGEF1 RIBC1 SNAPC5 TAB2 TAX1BP1 TSNAX YJU2 ZC2HC1C ZNF655
Entrez ID		631	11117
HPRD ID		04494	00563
Ensembl ID		ENSG00000125864	ENSG00000138080
Uniprot IDs		B7Z999 B7ZAD2 Q12934	Q9Y6C2
PDB IDs			2KA3 2OII
Enriched GO Terms of Interacting Partners?
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