ZWINT and PHAX

Data Source:
BioGRID (two hybrid)

		ZWINT	PHAX
Description		ZW10 interacting kinetochore protein	phosphorylated adaptor for RNA export
Image		No pdb structure
GO Annotations	Cellular Component	Kinetochore Condensed Chromosome Kinetochore Nucleoplasm Cytoplasm Cytosol Nuclear Body Dendrite	Nucleus Nucleoplasm Centrosome Cytosol Cajal Body Neuronal Cell Body
	Molecular Function	Protein Binding Protein N-terminus Binding	RNA Binding Protein Binding Toxic Substance Binding
	Biological Process	Mitotic Sister Chromatid Segregation Mitotic Cell Cycle Checkpoint Mitotic Spindle Assembly Checkpoint Cell Division Establishment Of Localization In Cell	SnRNA Export From Nucleus Protein Transport SnRNA Transcription By RNA Polymerase II Nuclear Export
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation	snRNP Assembly RNA polymerase II transcribes snRNA genes
Drugs
Diseases
GWAS		Cardiac hypertrophy ( 21348951) Erosive tooth wear (severe vs non-severe) ( 29898447) Erosive tooth wear (severe vs none or mild) ( 29898447) Liver fibrosis (total hepatic collagen content) ( 32953199)	Colorectal cancer ( 30529582)
Interacting Genes		17 interacting genes: APP BCAS2 BFSP1 CCHCR1 CLU DSN1 FAM90A1 KRT75 LIG4 MAFB MIS12 MSGN1 NDC80 NUP54 PHAX TSG101 ZW10	16 interacting genes: ASPSCR1 CDC42 GADD45G GRB7 MKNK1 NSFL1C PDPK1 RAD23A RPS6KA1 STK3 TNFSF11 TULP3 UBXN2A VAV1 XPO1 ZWINT
Entrez ID		11130	51808
HPRD ID		18366	15122
Ensembl ID		ENSG00000122952	ENSG00000164902
Uniprot IDs		O95229	Q9H814
PDB IDs			2XC7
Enriched GO Terms of Interacting Partners?
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