ADAP1 and ANP32A

Data Source:
HPRD (in vitro)

		ADAP1	ANP32A
Description		ArfGAP with dual PH domains 1	acidic nuclear phosphoprotein 32 family member A
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GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Plasma Membrane Intracellular Membrane-bounded Organelle	Nucleus Nucleoplasm Cytoplasm Endoplasmic Reticulum Perinuclear Region Of Cytoplasm
	Molecular Function	GTPase Activator Activity Protein Binding Phosphatidylinositol-3,4,5-trisphosphate Binding Inositol 1,3,4,5 Tetrakisphosphate Binding Metal Ion Binding Phosphatidylinositol Bisphosphate Binding	RNA Binding Protein Binding Histone Binding
	Biological Process	Cell Surface Receptor Signaling Pathway Regulation Of GTPase Activity Positive Regulation Of GTPase Activity	Nucleocytoplasmic Transport Intracellular Signal Transduction Regulation Of Apoptotic Process Regulation Of MRNA Stability
Pathways		Nuclear signaling by ERBB4	HuR (ELAVL1) binds and stabilizes mRNA
Drugs
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) Lymphocyte counts ( 32888494) Lymphocyte percentage of white cells ( 32888494) Monocyte count ( 32888494) Platelet distribution width ( 32888494)	Esophageal cancer ( 21642993)
Interacting Genes		24 interacting genes: ANP32A AP3B2 CSNK1A1 DVL3 GADD45A GOLGA2 GSK3B NCL PIK3CA PLEKHF2 PRKCA PRKCE PRKCI PRKCZ PRKD1 PSME3 PURA RANBP9 RPS9 SDCBP2 SF3A3 SRSF2 SUB1 SUPV3L1	29 interacting genes: ADAP1 APEX1 ATXN1 AXIN1 CHAF1A E4F1 ELAVL1 H2AC20 H2BC21 H3-4 H3C1 H3C15 H4-16 H4C1 HSPB3 KPNA1 KPNA5 KPNA6 LHX3 MAP1B NSFL1C PCBP1 PGR PPARG PTPRC SET TAF1A THRB XPO1
Entrez ID		11033	8125
HPRD ID		09733	09014
Ensembl ID		ENSG00000105963	ENSG00000140350
Uniprot IDs		A8K3A2 B4DUZ7 O75689	A0A384P5U2 P39687
PDB IDs		3FEH 3FM8 3LJU 3MDB	2JE0 2JE1 4XOS
Enriched GO Terms of Interacting Partners?
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