ADAP1 and SUB1

Data Source:
HPRD (in vitro)

		ADAP1	SUB1
Description		ArfGAP with dual PH domains 1	SUB1 regulator of transcription
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GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Plasma Membrane Intracellular Membrane-bounded Organelle	Nucleus Nucleoplasm Transcription Regulator Complex Nucleolus Extracellular Exosome
	Molecular Function	GTPase Activator Activity Protein Binding Phosphatidylinositol-3,4,5-trisphosphate Binding Inositol 1,3,4,5 Tetrakisphosphate Binding Metal Ion Binding Phosphatidylinositol Bisphosphate Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Single-stranded DNA Binding Transcription Coactivator Activity RNA Binding Protein Binding Identical Protein Binding
	Biological Process	Cell Surface Receptor Signaling Pathway Regulation Of GTPase Activity Positive Regulation Of GTPase Activity	Regulation Of Transcription By RNA Polymerase II Negative Regulation Of DNA Metabolic Process Positive Regulation Of Transcription Initiation From RNA Polymerase II Promoter SMAD Protein Signal Transduction
Pathways		Nuclear signaling by ERBB4
Drugs
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) Lymphocyte counts ( 32888494) Lymphocyte percentage of white cells ( 32888494) Monocyte count ( 32888494) Platelet distribution width ( 32888494)	Metabolite levels ( 23823483) PR interval ( 32439900)
Interacting Genes		24 interacting genes: ANP32A AP3B2 CSNK1A1 DVL3 GADD45A GOLGA2 GSK3B NCL PIK3CA PLEKHF2 PRKCA PRKCE PRKCI PRKCZ PRKD1 PSME3 PURA RANBP9 RPS9 SDCBP2 SF3A3 SRSF2 SUB1 SUPV3L1	22 interacting genes: ADAP1 APP CBX5 CSNK2A1 CSTF2 EP300 GTF2A1L HNF4A HSF1 OTUD5 PCNA POLR2A POLR2B POU2AF1 PSIP1 RCOR1 REST SDCBP SP1 TAF1 TBP TP53
Entrez ID		11033	10923
HPRD ID		09733	02737
Ensembl ID		ENSG00000105963	ENSG00000113387
Uniprot IDs		A8K3A2 B4DUZ7 O75689	P53999 Q6IBA2
PDB IDs		3FEH 3FM8 3LJU 3MDB	1PCF 2C62 2PHE 4USG 6YCS
Enriched GO Terms of Interacting Partners?
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