IMMT and AKTIP

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		IMMT	AKTIP
Description		inner membrane mitochondrial protein	AKT interacting protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	SAM Complex Mitochondrion Mitochondrial Inner Membrane Mitochondrial Intermembrane Space Membrane MICOS Complex MIB Complex	Nucleus Cytosol Plasma Membrane HOPS Complex FHF Complex
	Molecular Function	RNA Binding Protein Binding	Protein Binding Ubiquitin-like Protein Transferase Activity Ubiquitin Conjugating Enzyme Activity
	Biological Process	Inner Mitochondrial Membrane Organization Cristae Formation Mitochondrial Calcium Ion Homeostasis	Protein Polyubiquitination Positive Regulation Of Protein Phosphorylation Apoptotic Process Cellular Response To DNA Damage Stimulus Endosome Organization Lysosome Organization Endosome To Lysosome Transport Protein Transport Protein Phosphopantetheinylation Positive Regulation Of Protein Binding Early Endosome To Late Endosome Transport
Pathways		Cristae formation
Drugs
Diseases
GWAS		Facial emotion recognition (sad faces) ( 28608620) Night sleep phenotypes ( 27126917)	Body mass index ( 26426971) Body mass index (age>50) ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971) Depressive symptoms (SSRI exposure interaction) ( 25649181) Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) Hip circumference adjusted for BMI ( 25673412) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858)
Interacting Genes		58 interacting genes: AKTIP ALB ANTKMT ARMCX3 ASCC2 ATXN1 BAG6 BMI1 C10orf88 C8orf33 CALM1 CCDC113 CCT5 CDC37 CHD3 CSTF2 DISC1 ECSIT EEF1A1 EP300 EXOSC10 FEZ1 FUBP1 HAP1 HIVEP1 HJURP HMOX2 HNRNPD HTRA2 KDM1A KIF22 KPNA2 LRIF1 MRPL44 NDEL1 NDUFB9 NEK2 NIPSNAP3A NOS3 PFDN1 PIAS4 PLA2G15 PPOX PRRC2A RER1 SDHAF2 SMN1 SNAPIN SRRT STMN4 STX5 TAF1D TK1 TNNT1 TRAF3IP1 TUBGCP3 TXNDC9 UBQLN4	34 interacting genes: ACTN2 AKT1 ASS1 CEP126 CTBP2 DMXL2 DZIP3 EXOC7 FHIP1B GTF3C1 HOOK1 HOOK2 HOOK3 IMMT IPO7 LMNA MAP3K7 MARCHF5 MATR3 NEB PDE4DIP PDPK1 POLA2 RASGRF2 RPA1 TRIM23 TRIM32 TRIM41 TWNK UPF2 UTP14A VPS16 VPS18 VPS41
Entrez ID		10989	64400
HPRD ID		02658	07467
Ensembl ID		ENSG00000132305	ENSG00000166971
Uniprot IDs		Q16891	A0A024R6S6 A0A024R6T5 Q9H8T0
PDB IDs
Enriched GO Terms of Interacting Partners?
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