AKTIP and EXOC7

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		AKTIP	EXOC7
Description		AKT interacting protein	exocyst complex component 7
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol Plasma Membrane HOPS Complex FHF Complex	Exocyst Microtubule Organizing Center Cytosol Plasma Membrane Membrane Growth Cone Membrane Centriolar Satellite Flemming Body
	Molecular Function	Protein Binding Ubiquitin-like Protein Transferase Activity Ubiquitin Conjugating Enzyme Activity	Protein Binding
	Biological Process	Protein Polyubiquitination Positive Regulation Of Protein Phosphorylation Apoptotic Process Cellular Response To DNA Damage Stimulus Endosome Organization Lysosome Organization Endosome To Lysosome Transport Protein Transport Protein Phosphopantetheinylation Positive Regulation Of Protein Binding Early Endosome To Late Endosome Transport	Exocytosis Protein Transport Regulation Of Macroautophagy Regulation Of Entry Of Bacterium Into Host Cell
Pathways			Translocation of SLC2A4 (GLUT4) to the plasma membrane Insulin processing VxPx cargo-targeting to cilium
Drugs
Diseases
GWAS		Body mass index ( 26426971) Body mass index (age>50) ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971) Depressive symptoms (SSRI exposure interaction) ( 25649181) Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) Hip circumference adjusted for BMI ( 25673412) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858)	Body size at age 10 ( 32376654)
Interacting Genes		34 interacting genes: ACTN2 AKT1 ASS1 CEP126 CTBP2 DMXL2 DZIP3 EXOC7 FHIP1B GTF3C1 HOOK1 HOOK2 HOOK3 IMMT IPO7 LMNA MAP3K7 MARCHF5 MATR3 NEB PDE4DIP PDPK1 POLA2 RASGRF2 RPA1 TRIM23 TRIM32 TRIM41 TWNK UPF2 UTP14A VPS16 VPS18 VPS41	37 interacting genes: AKTIP ARFGEF2 ARPC1A BBS1 BBS2 BBS4 CCDC85B CCHCR1 CDC5L CT55 DISC1 DLG3 EXOC2 EXOC4 FBXO28 GRIN2B HGS IFT20 KDM1A KIFC3 KXD1 MSGN1 PLEKHF2 PRPF19 RALA RALY RHOQ RTN4IP1 SAPCD2 SMARCE1 SNAPIN SSC5D TRAF4 TRIM54 USHBP1 YAE1 ZC3H14
Entrez ID		64400	23265
HPRD ID		07467	16292
Ensembl ID		ENSG00000166971	ENSG00000182473
Uniprot IDs		A0A024R6S6 A0A024R6T5 Q9H8T0	B4DJ07 B5MCY9 Q63HP7 Q9UPT5
PDB IDs
Enriched GO Terms of Interacting Partners?
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