AKTIP and IPO7

Data Source:
BioGRID (pull down)

		AKTIP	IPO7
Description		AKT interacting protein	importin 7
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol Plasma Membrane HOPS Complex FHF Complex	Nuclear Envelope Nuclear Pore Nucleoplasm Cytosol Membrane
	Molecular Function	Protein Binding Ubiquitin-like Protein Transferase Activity Ubiquitin Conjugating Enzyme Activity	Transporter Activity Protein Binding GTPase Regulator Activity Small GTPase Binding Histone Binding SMAD Binding
	Biological Process	Protein Polyubiquitination Positive Regulation Of Protein Phosphorylation Apoptotic Process Cellular Response To DNA Damage Stimulus Endosome Organization Lysosome Organization Endosome To Lysosome Transport Protein Transport Protein Phosphopantetheinylation Positive Regulation Of Protein Binding Early Endosome To Late Endosome Transport	Protein Import Into Nucleus Signal Transduction Viral Process Innate Immune Response Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
Pathways
Drugs
Diseases
GWAS		Body mass index ( 26426971) Body mass index (age>50) ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971) Depressive symptoms (SSRI exposure interaction) ( 25649181) Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) Hip circumference adjusted for BMI ( 25673412) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858)	Interleukin-10 levels ( 22205395)
Interacting Genes		34 interacting genes: ACTN2 AKT1 ASS1 CEP126 CTBP2 DMXL2 DZIP3 EXOC7 FHIP1B GTF3C1 HOOK1 HOOK2 HOOK3 IMMT IPO7 LMNA MAP3K7 MARCHF5 MATR3 NEB PDE4DIP PDPK1 POLA2 RASGRF2 RPA1 TRIM23 TRIM32 TRIM41 TWNK UPF2 UTP14A VPS16 VPS18 VPS41	11 interacting genes: AKTIP H1-0 KPNB1 LIMS1 LINC01554 PTEN RAN RPL23A RPL5 RPS7 SRP19
Entrez ID		64400	10527
HPRD ID		07467	09280
Ensembl ID		ENSG00000166971	ENSG00000205339
Uniprot IDs		A0A024R6S6 A0A024R6T5 Q9H8T0	B3KNG9 O95373
PDB IDs
Enriched GO Terms of Interacting Partners?
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