KDELR1 and ARFGAP1

Data Source:
HPRD (in vivo, in vitro)

		KDELR1	ARFGAP1
Description		KDEL endoplasmic reticulum protein retention receptor 1	ADP ribosylation factor GTPase activating protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Cis-Golgi Network Integral Component Of Membrane Transport Vesicle COPI-coated Vesicle Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane	Golgi Membrane Cytosol Synapse
	Molecular Function	KDEL Sequence Binding Protein Binding ER Retention Sequence Binding	GTPase Activator Activity Protein Binding Metal Ion Binding
	Biological Process	Protein Retention In ER Lumen Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Protein Transport	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Protein Transport Regulation Of Endocytosis Regulation Of ARF Protein Signal Transduction IRE1-mediated Unfolded Protein Response Positive Regulation Of GTPase Activity
Pathways		COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic	XBP1(S) activates chaperone genes COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic Clathrin-mediated endocytosis
Drugs
Diseases
GWAS
Interacting Genes		12 interacting genes: ARF1 ARFGAP1 CCR9 COPB1 DLG2 DLG3 F2RL1 GPR35 KRT34 LIG4 PRKACA SEC23B	34 interacting genes: AGTR1 APOB APOC3 APOE APP ARF1 ASB10 COPA COPS5 CSNK1D CYTH2 FOS GABARAPL2 GRN HRAS KDELR1 KRTAP10-9 KRTAP3-2 KRTAP9-2 LRRK2 MAP1LC3B MED27 PRKACB RAB23 RABGAP1L RASIP1 REEP5 RFC3 RGS2 RPL11 SMN1 TK1 TMED2 TRIM23
Entrez ID		10945	55738
HPRD ID		00569	06443
Ensembl ID		ENSG00000105438	ENSG00000101199
Uniprot IDs		P24390	Q53F62 Q8N6T3
PDB IDs			3DWD 3O47
Enriched GO Terms of Interacting Partners?
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