CTCF and RALA

Data Source:
BioGRID (two hybrid)

		CTCF	RALA
Description		CCCTC-binding factor	RAS like proto-oncogene A
Image
GO Annotations	Cellular Component	Chromosome, Centromeric Region Condensed Chromosome Nucleus Nucleoplasm Nucleolus	Plasma Membrane Focal Adhesion Cell Surface Endocytic Vesicle Cytoplasmic Vesicle Membrane Cleavage Furrow Extracellular Exosome Flemming Body
	Molecular Function	Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Zinc Ion Binding Chromatin Insulator Sequence Binding Sequence-specific DNA Binding	GTPase Activity Protein Binding GTP Binding Myosin Binding GDP Binding Ubiquitin Protein Ligase Binding Edg-2 Lysophosphatidic Acid Receptor Binding ATPase Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II DNA Methylation Regulation Of Gene Expression By Genetic Imprinting Regulation Of Transcription By RNA Polymerase II Chromosome Segregation Negative Regulation Of Cell Population Proliferation Maintenance Of DNA Methylation Positive Regulation Of Gene Expression Nucleosome Positioning Regulation Of Histone Methylation Regulation Of Histone Acetylation Regulation Of Gene Expression, Epigenetic Regulation Of Molecular Function, Epigenetic Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Regulation Of Centromeric Sister Chromatid Cohesion Protein Localization To Chromosome, Centromeric Region Genetic Imprinting	Neural Tube Closure Exocytosis Chemotaxis Cell Cycle Signal Transduction Ras Protein Signal Transduction Regulation Of Exocytosis Actin Cytoskeleton Reorganization Interleukin-12-mediated Signaling Pathway Cell Division Positive Regulation Of Filopodium Assembly Membrane Raft Localization Membrane Organization
Pathways		Activation of anterior HOX genes in hindbrain development during early embryogenesis	Translocation of SLC2A4 (GLUT4) to the plasma membrane p38MAPK events Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation
Drugs			Guanosine-5'-Diphosphate
Diseases
GWAS		Elevated fasting plasma glucose ( 30004843) Eosinophil percentage of white cells ( 32888494) HDL cholesterol ( 19060911) Hemoglobin levels ( 32327693) Refractive error ( 32231278)
Interacting Genes		21 interacting genes: CHD1L CHD7 CHD8 HMGB1 MT-ND4 PARP1 POLR2A RAD51 RALA RHOU RXRA SIN3A SMAD3 SMAD4 SUZ12 THRB TRAF2 TRB YBX1 ZMYM4 ZMYM6	30 interacting genes: ARF1 CALM1 CNKSR2 CTCF EXOC1 EXOC2 EXOC3 EXOC4 EXOC5 EXOC6B EXOC7 EXOC8 FLNA GLS2 HSPB1 LSM2 PIH1D2 PLCD1 PLD1 PPP2R1B RAB34 RAB8B RALBP1 RALGPS1 RASSF5 REPS1 RGL2 RGL4 SMAD4 YBX3
Entrez ID		10664	5898
HPRD ID		05005	01549
Ensembl ID		ENSG00000102974	ENSG00000006451
Uniprot IDs		A0A2R8YFL0 P49711	P11233
PDB IDs		1X6H 2CT1 5K5H 5K5I 5K5J 5K5L 5KKQ 5T00 5T0U 5UND 5YEF 5YEG 5YEH 5YEL 6QNX	1UAD 1ZC3 1ZC4 2A78 2A9K 2BOV 6P0I 6P0J 6P0K 6P0L 6P0M 6P0N 6P0O
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?