RALA and RAB34

Data Source:
BioGRID (two hybrid)

		RALA	RAB34
Description		RAS like proto-oncogene A	RAB34, member RAS oncogene family
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Focal Adhesion Cell Surface Endocytic Vesicle Cytoplasmic Vesicle Membrane Cleavage Furrow Extracellular Exosome Flemming Body	Golgi Apparatus Golgi Stack Cilium Phagocytic Vesicle Membrane Vesicle Golgi Cisterna Ruffle Membrane Phagocytic Vesicle Perinuclear Region Of Cytoplasm Extracellular Exosome
	Molecular Function	GTPase Activity Protein Binding GTP Binding Myosin Binding GDP Binding Ubiquitin Protein Ligase Binding Edg-2 Lysophosphatidic Acid Receptor Binding ATPase Binding	GTPase Activity Protein Binding GTP Binding GTP-dependent Protein Binding Small GTPase Binding
	Biological Process	Neural Tube Closure Exocytosis Chemotaxis Cell Cycle Signal Transduction Ras Protein Signal Transduction Regulation Of Exocytosis Actin Cytoskeleton Reorganization Interleukin-12-mediated Signaling Pathway Cell Division Positive Regulation Of Filopodium Assembly Membrane Raft Localization Membrane Organization	Endocytosis Antigen Processing And Presentation Cell Projection Organization Lysosome Localization Golgi To Plasma Membrane Protein Transport Macropinocytosis Positive Regulation Of Smoothened Signaling Pathway Protein Localization To Plasma Membrane Phagosome Maturation Phagosome-lysosome Fusion
Pathways		Translocation of SLC2A4 (GLUT4) to the plasma membrane p38MAPK events Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation	RAB geranylgeranylation
Drugs		Guanosine-5'-Diphosphate
Diseases
GWAS			Urate levels in lean individuals ( 25811787)
Interacting Genes		30 interacting genes: ARF1 CALM1 CNKSR2 CTCF EXOC1 EXOC2 EXOC3 EXOC4 EXOC5 EXOC6B EXOC7 EXOC8 FLNA GLS2 HSPB1 LSM2 PIH1D2 PLCD1 PLD1 PPP2R1B RAB34 RAB8B RALBP1 RALGPS1 RASSF5 REPS1 RGL2 RGL4 SMAD4 YBX3	8 interacting genes: CA8 RABGAP1L RALA RILP SMAD1 SMAD2 SMAD4 TGFBR1
Entrez ID		5898	83871
HPRD ID		01549	06701
Ensembl ID		ENSG00000006451	ENSG00000109113
Uniprot IDs		P11233	A0A024QZ68 B4DNC0 E7ES60 P0DI83 Q96PJ7 Q9BZG1
PDB IDs		1UAD 1ZC3 1ZC4 2A78 2A9K 2BOV 6P0I 6P0J 6P0K 6P0L 6P0M 6P0N 6P0O
Enriched GO Terms of Interacting Partners?
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