CTCF and TRB

Data Source:
BioGRID (pull down, pull down)

		CTCF	TRB
Description		CCCTC-binding factor	T cell receptor beta locus
Image			No pdb structure
GO Annotations	Cellular Component	Chromosome, Centromeric Region Condensed Chromosome Nucleus Nucleoplasm Nucleolus	Integral Component Of Membrane Alpha-beta T Cell Receptor Complex
	Molecular Function	Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Zinc Ion Binding Chromatin Insulator Sequence Binding Sequence-specific DNA Binding	Signaling Receptor Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II DNA Methylation Regulation Of Gene Expression By Genetic Imprinting Regulation Of Transcription By RNA Polymerase II Chromosome Segregation Negative Regulation Of Cell Population Proliferation Maintenance Of DNA Methylation Positive Regulation Of Gene Expression Nucleosome Positioning Regulation Of Histone Methylation Regulation Of Histone Acetylation Regulation Of Gene Expression, Epigenetic Regulation Of Molecular Function, Epigenetic Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Regulation Of Centromeric Sister Chromatid Cohesion Protein Localization To Chromosome, Centromeric Region Genetic Imprinting	Detection Of Tumor Cell T Cell Mediated Cytotoxicity Directed Against Tumor Cell Target
Pathways		Activation of anterior HOX genes in hindbrain development during early embryogenesis
Drugs
Diseases
GWAS		Elevated fasting plasma glucose ( 30004843) Eosinophil percentage of white cells ( 32888494) HDL cholesterol ( 19060911) Hemoglobin levels ( 32327693) Refractive error ( 32231278)	Narcolepsy ( 24204295)
Interacting Genes		21 interacting genes: CHD1L CHD7 CHD8 HMGB1 MT-ND4 PARP1 POLR2A RAD51 RALA RHOU RXRA SIN3A SMAD3 SMAD4 SUZ12 THRB TRAF2 TRB YBX1 ZMYM4 ZMYM6	14 interacting genes: CD1D CD247 CD3D CD3E CD3G CTCF HLA-A HLA-B HLA-DRB1 NCOA6 TAF1B TRA TRAT1 TRD
Entrez ID		10664	6957
HPRD ID		05005	01739
Ensembl ID		ENSG00000102974
Uniprot IDs		A0A2R8YFL0 P49711
PDB IDs		1X6H 2CT1 5K5H 5K5I 5K5J 5K5L 5KKQ 5T00 5T0U 5UND 5YEF 5YEG 5YEH 5YEL 6QNX
Enriched GO Terms of Interacting Partners?
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