CTCF and CHD1L

Data Source:
BioGRID (two hybrid)

		CTCF	CHD1L
Description		CCCTC-binding factor	chromodomain helicase DNA binding protein 1 like
Image			No pdb structure
GO Annotations	Cellular Component	Chromosome, Centromeric Region Condensed Chromosome Nucleus Nucleoplasm Nucleolus	Nucleus Nucleoplasm Cytosol Plasma Membrane
	Molecular Function	Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Zinc Ion Binding Chromatin Insulator Sequence Binding Sequence-specific DNA Binding	Nucleotide Binding DNA Helicase Activity Protein Binding ATP Binding ATPase Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II DNA Methylation Regulation Of Gene Expression By Genetic Imprinting Regulation Of Transcription By RNA Polymerase II Chromosome Segregation Negative Regulation Of Cell Population Proliferation Maintenance Of DNA Methylation Positive Regulation Of Gene Expression Nucleosome Positioning Regulation Of Histone Methylation Regulation Of Histone Acetylation Regulation Of Gene Expression, Epigenetic Regulation Of Molecular Function, Epigenetic Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Regulation Of Centromeric Sister Chromatid Cohesion Protein Localization To Chromosome, Centromeric Region Genetic Imprinting	Nucleotide-excision Repair, DNA Duplex Unwinding DNA Repair Nucleotide-excision Repair, Preincision Complex Stabilization Nucleotide-excision Repair, Preincision Complex Assembly Nucleotide-excision Repair, DNA Incision, 3'-to Lesion Nucleotide-excision Repair, DNA Incision, 5'-to Lesion Chromatin Remodeling Cellular Response To DNA Damage Stimulus Nucleotide-excision Repair, DNA Incision Global Genome Nucleotide-excision Repair
Pathways		Activation of anterior HOX genes in hindbrain development during early embryogenesis	Formation of Incision Complex in GG-NER Dual Incision in GG-NER
Drugs
Diseases
GWAS		Elevated fasting plasma glucose ( 30004843) Eosinophil percentage of white cells ( 32888494) HDL cholesterol ( 19060911) Hemoglobin levels ( 32327693) Refractive error ( 32231278)	Height ( 31562340) Protein quantitative trait loci ( 18464913) Type 2 diabetes ( 25760438)
Interacting Genes		21 interacting genes: CHD1L CHD7 CHD8 HMGB1 MT-ND4 PARP1 POLR2A RAD51 RALA RHOU RXRA SIN3A SMAD3 SMAD4 SUZ12 THRB TRAF2 TRB YBX1 ZMYM4 ZMYM6	5 interacting genes: BAALC CTCF NR4A1 SCYL1 SRPK2
Entrez ID		10664	9557
HPRD ID		05005	09880
Ensembl ID		ENSG00000102974	ENSG00000131778
Uniprot IDs		A0A2R8YFL0 P49711	A0A0A0MRH8 A0A0A0MSH9 Q86WJ1
PDB IDs		1X6H 2CT1 5K5H 5K5I 5K5J 5K5L 5KKQ 5T00 5T0U 5UND 5YEF 5YEG 5YEH 5YEL 6QNX
Enriched GO Terms of Interacting Partners?
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