TBL3 and USP11

Data Source:
HPRD (two hybrid)

		TBL3	USP11
Description		transducin beta like 3	ubiquitin specific peptidase 11
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Nucleolus 90S Preribosome Small-subunit Processome	Nucleus Nucleoplasm Chromosome Cytosol
	Molecular Function	RNA Binding Protein Binding U3 SnoRNA Binding	RNA Polymerase II Transcription Corepressor Binding Cysteine-type Endopeptidase Activity Thiol-dependent Ubiquitin-specific Protease Activity Protein Binding
	Biological Process	Endonucleolytic Cleavage To Generate Mature 5'-end Of SSU-rRNA From (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Endonucleolytic Cleavage In 5'-ETS Of Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) RRNA Processing	Ubiquitin-dependent Protein Catabolic Process Viral Process Protein Deubiquitination Protein Phosphopantetheinylation
Pathways		rRNA modification in the nucleus and cytosol Major pathway of rRNA processing in the nucleolus and cytosol	Association of TriC/CCT with target proteins during biosynthesis Ub-specific processing proteases
Drugs
Diseases
GWAS
Interacting Genes		11 interacting genes: AHR APPBP2 AURKB CACNB4 CUL4B DHX30 ITSN2 NR2E3 SFN URM1 USP11	21 interacting genes: BMI1 BRCA2 CBX8 CDKN1A DECR2 EIF4B LIMS1 LLGL1 MBD3 MTA2 PCGF2 PML RANBP9 RELB RNF2 RPS6KB1 SETDB1 SUMO2 TBL3 TP53 UBC
Entrez ID		10607	8237
HPRD ID		09327	02081
Ensembl ID		ENSG00000183751	ENSG00000102226
Uniprot IDs		Q12788	B4DGK3 P51784
PDB IDs			4MEL 5OK6
Enriched GO Terms of Interacting Partners?
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