ANP32B and KPNA5

Data Source:
BioGRID (two hybrid)

		ANP32B	KPNA5
Description		acidic nuclear phosphoprotein 32 family member B	karyopherin subunit alpha 5
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Extracellular Exosome	Nucleus Nucleoplasm Cytosol
	Molecular Function	Protein Binding Histone Binding RNA Polymerase Binding	Protein Binding Nuclear Localization Sequence Binding Nuclear Import Signal Receptor Activity
	Biological Process	Vasculature Development Nucleosome Assembly Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Ventricular System Development Regulation Of Apoptotic Process Negative Regulation Of Cell Differentiation Positive Regulation Of Protein Export From Nucleus Inner Ear Development Roof Of Mouth Development	NLS-bearing Protein Import Into Nucleus Modulation By Virus Of Host Cellular Process
Pathways			ISG15 antiviral mechanism NS1 Mediated Effects on Host Pathways
Drugs
Diseases
GWAS		Alopecia areata ( 25608926) Coronary artery disease ( 29212778) Eosinophil counts ( 32888494) Immature fraction of reticulocytes ( 27863252) Mean corpuscular hemoglobin ( 32888494 27863252) Mean corpuscular volume ( 32888494) Red blood cell count ( 32888494 27863252) Serum thyroid-stimulating hormone levels ( 25436638)	Early cardiac repolarization ( 31600170) Telomere length ( 21460395)
Interacting Genes		43 interacting genes: AIM2 APC APP AURKA BAX BCL10 BEND7 BUB1 CHAF1A CSNK2A1 DCC DNTTIP1 ELAVL1 ESR1 FAM217B FAM3A FBXW7 H2AC1 H2BC1 H3C1 H4C1 HNF4A KLF5 KPNA1 KPNA5 KPNA6 MCC MEOX2 MLH3 MYNN PMS2 POLR1A PTEN PTPN12 PTPRJ SDCBP SMAD2 SMARCD1 STK11 TLR2 UCHL5 XPO1 YAF2	28 interacting genes: ANP32A ANP32B ARNT BRMS1 CDKN1B DCPS EPAS1 FAM214B FBXO7 HIF1A HNRNPC IL32 KAT5 LMNB1 MLH1 NMNAT1 NRF1 NUP50 POLR3C POU6F2 RAD52 RBBP4 SPOP SPOPL TSEN54 TWIST1 WT1 ZNF326
Entrez ID		10541	3841
HPRD ID		09803	05179
Ensembl ID		ENSG00000136938	ENSG00000196911
Uniprot IDs		Q92688	O15131
PDB IDs		2ELL 2RR6	4U2X
Enriched GO Terms of Interacting Partners?
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