DNAJB6 and ASAP1

Data Source:
BioGRID (two hybrid)

		DNAJB6	ASAP1
Description		DnaJ heat shock protein family (Hsp40) member B6	ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol Membrane Z Disc Perinuclear Region Of Cytoplasm	Podosome Cytosol Cell Projection Membrane Dendritic Spine
	Molecular Function	ATPase Activator Activity Protein Binding Heat Shock Protein Binding Unfolded Protein Binding Chaperone Binding	Phosphatidylserine Binding GTPase Activator Activity Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding Phosphatidylinositol-3,4,5-trisphosphate Binding Cadherin Binding Metal Ion Binding
	Biological Process	Protein Folding Positive Regulation Of ATPase Activity Regulation Of Protein Localization Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Intermediate Filament Organization Negative Regulation Of Inclusion Body Assembly Regulation Of Cellular Response To Heat	Positive Regulation Of GTPase Activity Cilium Assembly Negative Regulation Of Dendritic Spine Development Positive Regulation Of Podosome Assembly Positive Regulation Of Membrane Tubulation
Pathways		Regulation of HSF1-mediated heat shock response	VxPx cargo-targeting to cilium VxPx cargo-targeting to cilium
Drugs
Diseases
GWAS		Body mass index ( 28552196) Retinal detachment or retinal break ( 31816047) Waist circumference ( 28552196)	Diisocyanate-induced asthma ( 25918132) Mean corpuscular volume ( 32888494) Mean platelet volume ( 32888494 27863252) Multiple sclerosis ( 19525955) Nevus count or cutaneous melanoma ( 32341527) Platelet count ( 27863252) Platelet distribution width ( 32888494) Post bronchodilator FEV1 in COPD ( 26634245) Progressive supranuclear palsy ( 30089514) Refractive error ( 32231278) Tuberculosis ( 25774636) Waist circumference adjusted for body mass index ( 28552196)
Interacting Genes		23 interacting genes: ANKRD1 APP ASAP1 BRMS1 CAND2 DYSF KRT18 MAP3K1 MLF1 MLF2 MRTO4 MYBPC1 MYOM1 PGM1 PIK3CA POLR1D PTEN SGCG SKAP2 SUPT6H TTN TUBGCP3 USP8	15 interacting genes: ARF1 ARF6 CBL CRK DNAJB6 GRB2 HCK PACSIN3 PTK2 PTK2B PXN RAB11FIP3 REPS2 SH3KBP1 SRC
Entrez ID		10049	50807
HPRD ID		07107	05809
Ensembl ID		ENSG00000105993	ENSG00000153317
Uniprot IDs		A0A0J9YX62 O75190	A0A0A0MRE5 Q9ULH1
PDB IDs		6U3R 6U3S	2D1X 2DA0 2ED1 2RQT 2RQU
Enriched GO Terms of Interacting Partners?
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