ASAP1 and RAB11FIP3

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology, pull down)

		ASAP1	RAB11FIP3
Description		ArfGAP with SH3 domain, ankyrin repeat and PH domain 1	RAB11 family interacting protein 3
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GO Annotations	Cellular Component	Podosome Cytosol Cell Projection Membrane Dendritic Spine	Nucleoplasm Mitochondrion Endosome Centrosome Cytosol Endocytic Vesicle Midbody Cleavage Furrow Centriolar Satellite Intracellular Membrane-bounded Organelle Intercellular Bridge Recycling Endosome Recycling Endosome Membrane
	Molecular Function	Phosphatidylserine Binding GTPase Activator Activity Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding Phosphatidylinositol-3,4,5-trisphosphate Binding Cadherin Binding Metal Ion Binding	Calcium Ion Binding Protein Binding Small GTPase Binding Protein Homodimerization Activity Dynein Light Intermediate Chain Binding
	Biological Process	Positive Regulation Of GTPase Activity Cilium Assembly Negative Regulation Of Dendritic Spine Development Positive Regulation Of Podosome Assembly Positive Regulation Of Membrane Tubulation	Cell Cycle Vesicle-mediated Transport Endocytic Recycling Regulation Of Cytokinesis Cell Division Protein Localization To Cilium Negative Regulation Of Adiponectin Secretion
Pathways		VxPx cargo-targeting to cilium VxPx cargo-targeting to cilium	VxPx cargo-targeting to cilium
Drugs
Diseases
GWAS		Diisocyanate-induced asthma ( 25918132) Mean corpuscular volume ( 32888494) Mean platelet volume ( 32888494 27863252) Multiple sclerosis ( 19525955) Nevus count or cutaneous melanoma ( 32341527) Platelet count ( 27863252) Platelet distribution width ( 32888494) Post bronchodilator FEV1 in COPD ( 26634245) Progressive supranuclear palsy ( 30089514) Refractive error ( 32231278) Tuberculosis ( 25774636) Waist circumference adjusted for body mass index ( 28552196)	Coronary artery calcified atherosclerotic plaque score in type 2 diabetes ( 29221444) Heel bone mineral density ( 30598549) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mean platelet volume ( 32888494) Platelet count ( 32888494 27863252) Platelet distribution width ( 32888494 27863252) Plateletcrit ( 32888494)
Interacting Genes		15 interacting genes: ARF1 ARF6 CBL CRK DNAJB6 GRB2 HCK PACSIN3 PTK2 PTK2B PXN RAB11FIP3 REPS2 SH3KBP1 SRC	9 interacting genes: ARF4 ARF5 ARF6 ASAP1 RAB11A RAB11B RAB11FIP4 RAB25 TOMM34
Entrez ID		50807	9727
HPRD ID		05809	18521
Ensembl ID		ENSG00000153317	ENSG00000090565
Uniprot IDs		A0A0A0MRE5 Q9ULH1	O75154
PDB IDs		2D1X 2DA0 2ED1 2RQT 2RQU	2D7C 2HV8 4D0M 4UJ3 4UJ4
Enriched GO Terms of Interacting Partners?
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