HMGXB4 and TSPYL2

Data Source:
BioGRID (two hybrid)

		HMGXB4	TSPYL2
Description		HMG-box containing 4	TSPY like 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	NURF Complex	Chromatin Nucleus Nucleoplasm Nucleolus Cytoplasm
	Molecular Function	DNA Binding Protein Binding Identical Protein Binding	RDNA Binding Chromatin Binding Protein Binding Histone Binding
	Biological Process	Endosome To Lysosome Transport Wnt Signaling Pathway Negative Regulation Of Wnt Signaling Pathway	Nucleosome Assembly Cell Cycle Negative Regulation Of DNA Replication Regulation Of Signal Transduction Negative Regulation Of Cell Growth IRE1-mediated Unfolded Protein Response Negative Regulation Of Cell Cycle Regulation Of Protein Kinase Activity
Pathways			XBP1(S) activates chaperone genes
Drugs
Diseases
GWAS		Hip circumference adjusted for BMI ( 25673412) Platelet count ( 32888494) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971) Waist-to-hip ratio adjusted for body mass index ( 25673412)
Interacting Genes		24 interacting genes: AKAP17A CREBBP EPM2A H3-4 HABP4 INO80B JMJD6 LENG8 MX1 NKAPD1 NR1H2 PIAS2 SRPK2 STAC3 STRBP SUMO2 TENT5B TNNT1 TSC22D1 TSPYL2 UBE2I UBL5 UROD ZCCHC10	46 interacting genes: ABT1 AEBP2 APTX CASK CCNB1 CDK1 CDK2 CDK4 CEP19 COIL CREBBP CSNK2A1 EEF1A1 GFI1B H2BC15 HMGXB4 INO80B KMT5B LMO2 LNX1 MCRS1 NOL12 NOP53 PHF19 RBM15 RNF151 RPS25 SIRT6 SNIP1 TBC1D26 TMA16 TNNT1 TSPYL1 XAGE1A XAGE1B ZBTB24 ZBTB48 ZFP1 ZFP91 ZNF280C ZNF286A ZNF329 ZNF524 ZNF687 ZNF775 ZNF835
Entrez ID		10042	64061
HPRD ID		05267	06713
Ensembl ID		ENSG00000100281	ENSG00000184205
Uniprot IDs		Q7Z641 Q9UGU5	Q9H2G4
PDB IDs
Enriched GO Terms of Interacting Partners?
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