HMGXB4 and STAC3

Data Source:
BioGRID (two hybrid)

		HMGXB4	STAC3
Description		HMG-box containing 4	SH3 and cysteine rich domain 3
Image		No pdb structure
GO Annotations	Cellular Component	NURF Complex	Nucleoplasm Cytosol Voltage-gated Calcium Channel Complex T-tubule Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane Synapse
	Molecular Function	DNA Binding Protein Binding Identical Protein Binding	Protein Binding Identical Protein Binding Metal Ion Binding
	Biological Process	Endosome To Lysosome Transport Wnt Signaling Pathway Negative Regulation Of Wnt Signaling Pathway	Skeletal Muscle Contraction Neuromuscular Synaptic Transmission Intracellular Signal Transduction Skeletal Muscle Fiber Development Positive Regulation Of Voltage-gated Calcium Channel Activity Positive Regulation Of Protein Localization To Plasma Membrane
Pathways
Drugs
Diseases
GWAS		Hip circumference adjusted for BMI ( 25673412) Platelet count ( 32888494) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971) Waist-to-hip ratio adjusted for body mass index ( 25673412)	Asthma ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Schizophrenia ( 25056061 29483656)
Interacting Genes		24 interacting genes: AKAP17A CREBBP EPM2A H3-4 HABP4 INO80B JMJD6 LENG8 MX1 NKAPD1 NR1H2 PIAS2 SRPK2 STAC3 STRBP SUMO2 TENT5B TNNT1 TSC22D1 TSPYL2 UBE2I UBL5 UROD ZCCHC10	38 interacting genes: ANKRD36 BAZ2B C1orf35 CSNK2A1 DIP2A EAF1 EAF2 ENKD1 FAM124A FAM133A FAM90A1 FAM9A FGF11 FGF12 GAS8 GIGYF1 GRB7 HMGXB4 INO80B JMJD6 L3MBTL2 MAB21L3 MFAP1 NKAPD1 NSD3 PPARA RPL22 RPL9 RPS25 SPANXN2 SPANXN3 SREK1IP1 TCEA2 TNFAIP8L1 U2AF2 VCX2 ZCCHC10 ZGPAT
Entrez ID		10042	246329
HPRD ID		05267	11606
Ensembl ID		ENSG00000100281	ENSG00000185482
Uniprot IDs		Q7Z641 Q9UGU5	A0A024RB38 Q96MF2
PDB IDs			2DB6 6B29 6UY7 6UY8 6UY9
Enriched GO Terms of Interacting Partners?
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