MMGT1 and ORMDL2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		MMGT1	ORMDL2
Description		membrane magnesium transporter 1	ORMDL sphingolipid biosynthesis regulator 2
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Early Endosome Golgi Apparatus Plasma Membrane Membrane Integral Component Of Membrane Integral Component Of Endoplasmic Reticulum Membrane Early Endosome Membrane EMC Complex	Endoplasmic Reticulum Integral Component Of Membrane SPOTS Complex
	Molecular Function	Protein Binding Magnesium Ion Transmembrane Transporter Activity Inorganic Cation Transmembrane Transporter Activity Membrane Insertase Activity	Protein Binding
	Biological Process	Magnesium Ion Transport Protein Insertion Into ER Membrane By Stop-transfer Membrane-anchor Sequence Tail-anchored Membrane Protein Insertion Into ER Membrane Magnesium Ion Transmembrane Transport	Ceramide Metabolic Process Cellular Sphingolipid Homeostasis Negative Regulation Of Ceramide Biosynthetic Process
Pathways		Miscellaneous transport and binding events	Sphingolipid de novo biosynthesis
Drugs
Diseases
GWAS			Refractive error ( 32231278)
Interacting Genes		51 interacting genes: ADGRE2 AGR3 ANKRD46 APP C4orf3 C5 C8A DEFB127 EMD FIS1 FXYD6 GPR25 GRM2 INSIG2 ITGAM LNPEP MFF MFSD3 MFSD5 MS4A13 NDUFA3 NINJ2 ORMDL2 PEX16 PLPP6 RUSF1 SEC22B SLC35B4 SLC35E4 SLC38A7 SLC7A14 STX12 STX1A STX1B STX3 STX6 STX8 TAS2R19 TECR THBD TMBIM6 TMED8 TMEM14A TMEM14C TMEM229B TMEM254 TMEM42 TMEM60 TMEM86B VRK2 YIF1A	22 interacting genes: AQP6 CD79A CREB3L1 CYB561 CYB5R3 DAPK1 EBP ELOVL4 FAM210B FCER1G GJA8 KCNJ6 MMGT1 RETREG3 RNF41 SCN3B SLC10A1 TMEM120A TMEM31 TMEM86B TMX2 ZDHHC15
Entrez ID		93380	29095
HPRD ID		06626	17802
Ensembl ID		ENSG00000169446	ENSG00000123353
Uniprot IDs		Q8N4V1	Q53FV1
PDB IDs		6WW7 6Z3W 7ADO 7ADP
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
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