MMGT1 and FXYD6

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		MMGT1	FXYD6
Description		membrane magnesium transporter 1	FXYD domain containing ion transport regulator 6
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Early Endosome Golgi Apparatus Plasma Membrane Membrane Integral Component Of Membrane Integral Component Of Endoplasmic Reticulum Membrane Early Endosome Membrane EMC Complex	Plasma Membrane Glutamatergic Synapse Integral Component Of Postsynaptic Membrane Integral Component Of Presynaptic Membrane
	Molecular Function	Protein Binding Magnesium Ion Transmembrane Transporter Activity Inorganic Cation Transmembrane Transporter Activity Membrane Insertase Activity	Molecular_function Protein Binding Sodium Channel Regulator Activity
	Biological Process	Magnesium Ion Transport Protein Insertion Into ER Membrane By Stop-transfer Membrane-anchor Sequence Tail-anchored Membrane Protein Insertion Into ER Membrane Magnesium Ion Transmembrane Transport	Ion Transport Biological_process Regulation Of Sodium Ion Transmembrane Transporter Activity
Pathways		Miscellaneous transport and binding events	Ion homeostasis Ion transport by P-type ATPases Potential therapeutics for SARS
Drugs
Diseases
GWAS			Hippocampal volume in Alzheimer's disease dementia ( 29274321) Myopia ( 27182965)
Interacting Genes		51 interacting genes: ADGRE2 AGR3 ANKRD46 APP C4orf3 C5 C8A DEFB127 EMD FIS1 FXYD6 GPR25 GRM2 INSIG2 ITGAM LNPEP MFF MFSD3 MFSD5 MS4A13 NDUFA3 NINJ2 ORMDL2 PEX16 PLPP6 RUSF1 SEC22B SLC35B4 SLC35E4 SLC38A7 SLC7A14 STX12 STX1A STX1B STX3 STX6 STX8 TAS2R19 TECR THBD TMBIM6 TMED8 TMEM14A TMEM14C TMEM229B TMEM254 TMEM42 TMEM60 TMEM86B VRK2 YIF1A	65 interacting genes: APCDD1L APH1A AQP6 ARL13B BCAR1 C4BPA CCDC90B CD74 CERS4 CLDN7 CLEC10A CREB3 CREB3L1 DERL2 EBP ELOVL2 ELOVL4 ERGIC3 FCER1G FFAR2 FPR2 GDF9 GJA8 GPR42 HAUS2 JAGN1 KCNJ6 LHFPL2 LHFPL5 LMNA MFF MGST3 MMGT1 OCIAD1 PEX12 PGRMC2 PPP1CC RBM48 RHBDL1 RHCG RNASEK SLC10A1 SLC10A6 SLC16A7 SLC30A2 SLC35C2 SLC35E1 SLC35E3 SLC39A2 SLC47A1 SVOP TLCD4 TLE1 TM4SF18 TMEM154 TMEM237 TMEM239 TMEM31 TMEM35A TMEM72 TMEM86B TMPPE TP53 TRIM27 UNC119
Entrez ID		93380	53826
HPRD ID		06626	09456
Ensembl ID		ENSG00000169446	ENSG00000137726
Uniprot IDs		Q8N4V1	A0A024R3J8 Q9H0Q3
PDB IDs		6WW7 6Z3W 7ADO 7ADP
Enriched GO Terms of Interacting Partners?
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