ORMDL2 and TMEM120A

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		ORMDL2	TMEM120A
Description		ORMDL sphingolipid biosynthesis regulator 2	transmembrane protein 120A
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Integral Component Of Membrane SPOTS Complex	Cellular_component Nuclear Inner Membrane Plasma Membrane Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding	Molecular_function Ion Channel Activity Protein Binding
	Biological Process	Ceramide Metabolic Process Cellular Sphingolipid Homeostasis Negative Regulation Of Ceramide Biosynthetic Process	Ion Transmembrane Transport Fat Cell Differentiation Detection Of Mechanical Stimulus Involved In Sensory Perception Of Pain Protein Homooligomerization Protein Heterooligomerization
Pathways		Sphingolipid de novo biosynthesis
Drugs
Diseases
GWAS		Refractive error ( 32231278)	Coffee consumption ( 25288136) Coffee consumption (cups per day) ( 25288136) Sarcoidosis ( 32826979)
Interacting Genes		22 interacting genes: AQP6 CD79A CREB3L1 CYB561 CYB5R3 DAPK1 EBP ELOVL4 FAM210B FCER1G GJA8 KCNJ6 MMGT1 RETREG3 RNF41 SCN3B SLC10A1 TMEM120A TMEM31 TMEM86B TMX2 ZDHHC15	24 interacting genes: AQP6 CYBRD1 FAM209A FBXO7 GOT1 GPRC5B HSD17B13 LEPROT LRRC25 ORMDL2 PAXIP1 PPP1CC PTAFR SCN3B STX1A STX2 TMEM14B TMEM35A TMEM86B TMX2 TPRG1 TSPAN18 UBC VKORC1
Entrez ID		29095	83862
HPRD ID		17802	15543
Ensembl ID		ENSG00000123353	ENSG00000189077
Uniprot IDs		Q53FV1	A0A087X266 Q9BXJ8
PDB IDs
Enriched GO Terms of Interacting Partners?
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