MMGT1 and STX8

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		MMGT1	STX8
Description		membrane magnesium transporter 1	syntaxin 8
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Early Endosome Golgi Apparatus Plasma Membrane Membrane Integral Component Of Membrane Integral Component Of Endoplasmic Reticulum Membrane Early Endosome Membrane EMC Complex	Lysosomal Membrane Endosome Early Endosome Late Endosome Endoplasmic Reticulum Trans-Golgi Network Cytosol Integral Component Of Plasma Membrane Endomembrane System Integral Component Of Membrane SNARE Complex Late Endosome Membrane Vesicle Phagocytic Vesicle Perinuclear Region Of Cytoplasm Recycling Endosome
	Molecular Function	Protein Binding Magnesium Ion Transmembrane Transporter Activity Inorganic Cation Transmembrane Transporter Activity Membrane Insertase Activity	SNARE Binding SNAP Receptor Activity Protein Binding Chloride Channel Inhibitor Activity Syntaxin Binding Ubiquitin Protein Ligase Binding
	Biological Process	Magnesium Ion Transport Protein Insertion Into ER Membrane By Stop-transfer Membrane-anchor Sequence Tail-anchored Membrane Protein Insertion Into ER Membrane Magnesium Ion Transmembrane Transport	Intracellular Protein Transport Vesicle Fusion Endosome To Lysosome Transport Early Endosome To Late Endosome Transport Vesicle Docking Cellular Response To Interferon-gamma Regulation Of Protein Localization To Plasma Membrane
Pathways		Miscellaneous transport and binding events
Drugs
Diseases
GWAS			Blood protein levels ( 30072576) Borderline personality disorder ( 28632202) Brain morphology (MOSTest) ( 32665545) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) HDL cholesterol change in response to fenofibrate in statin-treated type 2 diabetes ( 28736931) Obstructive sleep apnea trait (apnea hypopnea index) ( 29077507)
Interacting Genes		51 interacting genes: ADGRE2 AGR3 ANKRD46 APP C4orf3 C5 C8A DEFB127 EMD FIS1 FXYD6 GPR25 GRM2 INSIG2 ITGAM LNPEP MFF MFSD3 MFSD5 MS4A13 NDUFA3 NINJ2 ORMDL2 PEX16 PLPP6 RUSF1 SEC22B SLC35B4 SLC35E4 SLC38A7 SLC7A14 STX12 STX1A STX1B STX3 STX6 STX8 TAS2R19 TECR THBD TMBIM6 TMED8 TMEM14A TMEM14C TMEM229B TMEM254 TMEM42 TMEM60 TMEM86B VRK2 YIF1A	84 interacting genes: ACVR1 AMIGO1 AQP2 ASGR2 BCL2L13 BIK BSND CALM1 CD300E CD79A CERS4 CLDN9 CLN8 COPA CPLX4 CREB3 CREB3L1 DHRS9 DNAH9 EBP ERGIC3 FAM174A FAM209A FFAR2 FKBP7 FNDC9 GJA8 GJB1 GORAB GPR151 GPR152 GPR42 GPX8 JAGN1 JSRP1 KCNMB1 LMNA MCEE MCL1 MFF MGST2 MGST3 MMGT1 MS4A3 MTERF3 NAPA NAPG NCR3LG1 NDUFAF1 NDUFAF2 NSF PEX12 PSCA RETREG3 RNASEK SAR1A SCN3B SGPL1 SLC10A6 SLC18A1 SLC22A2 SSMEM1 STAR STMN4 STX1A STX2 STX4 STX5 STX7 TGFBR1 TMED8 TMEM14B TMEM179B TMEM205 TMEM237 TMEM86B TMPPE TMPRSS2 TSPAN12 VAMP5 VPS11 VPS18 VTI1B WDR91
Entrez ID		93380	9482
HPRD ID		06626	05012
Ensembl ID		ENSG00000169446	ENSG00000170310
Uniprot IDs		Q8N4V1	Q9UNK0
PDB IDs		6WW7 6Z3W 7ADO 7ADP
Enriched GO Terms of Interacting Partners?
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