MMGT1 and C8A

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		MMGT1	C8A
Description		membrane magnesium transporter 1	complement C8 alpha chain
Image
GO Annotations	Cellular Component	Golgi Membrane Early Endosome Golgi Apparatus Plasma Membrane Membrane Integral Component Of Membrane Integral Component Of Endoplasmic Reticulum Membrane Early Endosome Membrane EMC Complex	Extracellular Region Membrane Attack Complex Extracellular Space Membrane Extracellular Exosome Blood Microparticle
	Molecular Function	Protein Binding Magnesium Ion Transmembrane Transporter Activity Inorganic Cation Transmembrane Transporter Activity Membrane Insertase Activity	Complement Binding Protein Binding Protein-containing Complex Binding
	Biological Process	Magnesium Ion Transport Protein Insertion Into ER Membrane By Stop-transfer Membrane-anchor Sequence Tail-anchored Membrane Protein Insertion Into ER Membrane Magnesium Ion Transmembrane Transport	Immune Response Complement Activation Complement Activation, Alternative Pathway Complement Activation, Classical Pathway Cytolysis
Pathways		Miscellaneous transport and binding events	Terminal pathway of complement Regulation of Complement cascade
Drugs			Zinc Zinc acetate
Diseases
GWAS			Blood protein levels ( 28240269)
Interacting Genes		51 interacting genes: ADGRE2 AGR3 ANKRD46 APP C4orf3 C5 C8A DEFB127 EMD FIS1 FXYD6 GPR25 GRM2 INSIG2 ITGAM LNPEP MFF MFSD3 MFSD5 MS4A13 NDUFA3 NINJ2 ORMDL2 PEX16 PLPP6 RUSF1 SEC22B SLC35B4 SLC35E4 SLC38A7 SLC7A14 STX12 STX1A STX1B STX3 STX6 STX8 TAS2R19 TECR THBD TMBIM6 TMED8 TMEM14A TMEM14C TMEM229B TMEM254 TMEM42 TMEM60 TMEM86B VRK2 YIF1A	9 interacting genes: C8B C8G C9 CD59 GOLT1A GPR152 MMGT1 SLC10A1 SLC7A1
Entrez ID		93380	731
HPRD ID		06626	00409
Ensembl ID		ENSG00000169446	ENSG00000157131
Uniprot IDs		Q8N4V1	P07357
PDB IDs		6WW7 6Z3W 7ADO 7ADP	2QOS 2QQH 2RD7 3OJY 6H03 6H04
Enriched GO Terms of Interacting Partners?
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