CCL4 and SLC30A2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		CCL4	SLC30A2
Description		C-C motif chemokine ligand 4	solute carrier family 30 member 2
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space	Cytoplasm Lysosomal Membrane Late Endosome Plasma Membrane Integral Component Of Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Cytokine Activity Protein Binding Chemokine Activity CCR1 Chemokine Receptor Binding CCR5 Chemokine Receptor Binding Identical Protein Binding CCR Chemokine Receptor Binding	Zinc Ion Transmembrane Transporter Activity Protein Binding Identical Protein Binding
	Biological Process	Monocyte Chemotaxis Inflammatory Response Immune Response Cell Adhesion Establishment Or Maintenance Of Cell Polarity Signal Transduction G Protein-coupled Receptor Signaling Pathway Cell-cell Signaling Response To Virus Response To Toxic Substance Neutrophil Chemotaxis Positive Regulation Of GTPase Activity Negative Regulation By Host Of Viral Transcription Eosinophil Chemotaxis Lymphocyte Chemotaxis Positive Regulation Of Calcium-mediated Signaling Positive Regulation Of Calcium Ion Transport Chemokine-mediated Signaling Pathway Positive Regulation Of ERK1 And ERK2 Cascade Cellular Response To Interferon-gamma Cellular Response To Interleukin-1 Cellular Response To Tumor Necrosis Factor Positive Regulation Of Natural Killer Cell Chemotaxis	Response To Zinc Ion Regulation Of Sequestering Of Zinc Ion Positive Regulation Of Sequestering Of Zinc Ion Zinc Ion Transmembrane Transport
Pathways		Chemokine receptors bind chemokines G alpha (i) signalling events Interleukin-10 signaling	Zinc efflux and compartmentalization by the SLC30 family
Drugs
Diseases
GWAS		Blood protein levels in cardiovascular risk ( 28369058) Body mass index ( 26426971) Spherical equivalent or myopia (age of diagnosis) ( 29808027)
Interacting Genes		28 interacting genes: ACKR2 ARL13B CCL3 CCR1 CCR3 CCR5 CCR8 CNR2 CXCL8 GJA8 GPR152 GPRC5D HRAS MARCHF2 MRM1 PRRG2 SLC10A6 SLC18A1 SLC30A2 SLC30A8 SLC7A1 TAS2R5 TIMMDC1 TMEM14B TMEM179B TMEM31 TMEM86B UNC93A	66 interacting genes: ABHD16A ADAM33 AQP2 AQP6 ATP13A1 C5orf46 CCL4 CCL4L2 CD40 CD52 CD79A CD99L2 CPLX4 CREB3 CTSA CYB561D2 EBAG9 EMP3 EVI2B F11R FAM174A FDPS FFAR2 FXYD3 FXYD6 GALNT15 GJA5 GJB2 GJB5 GLB1 GOLT1A GPR161 GPR42 GPRC5D HGFAC KASH5 KCNN4 LMNA LTA LYVE1 MS4A13 NDUFAF1 NRM OPRM1 PCNX2 PLPPR1 PVR SEC22A SELL SERPING1 SLC10A6 SLC16A2 SLC18A1 SLC38A7 SLC39A2 SLC7A1 SLC7A8 TAS2R5 TM4SF18 TMEM107 TMEM52B TMEM60 TMEM86A TNFRSF12A TRARG1 YIPF2
Entrez ID		6351	7780
HPRD ID		01657	18057
Ensembl ID		ENSG00000275302	ENSG00000158014
Uniprot IDs		P13236	Q9BRI3
PDB IDs		1HUM 1HUN 1JE4 2FFK 2FIN 2X6L 3TN2 4RAL
Enriched GO Terms of Interacting Partners?
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