SLC30A2 and GLB1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		SLC30A2	GLB1
Description		solute carrier family 30 member 2	galactosidase beta 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Lysosomal Membrane Late Endosome Plasma Membrane Integral Component Of Membrane Intracellular Membrane-bounded Organelle	Extracellular Region Cytoplasm Vacuole Golgi Apparatus Azurophil Granule Lumen Lysosomal Lumen Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm Extracellular Exosome Ficolin-1-rich Granule Lumen
	Molecular Function	Zinc Ion Transmembrane Transporter Activity Protein Binding Identical Protein Binding	Beta-galactosidase Activity Protein Binding Galactoside Binding Protein Homodimerization Activity
	Biological Process	Response To Zinc Ion Regulation Of Sequestering Of Zinc Ion Positive Regulation Of Sequestering Of Zinc Ion Zinc Ion Transmembrane Transport	Glycosaminoglycan Catabolic Process Glycosphingolipid Metabolic Process Galactose Catabolic Process Keratan Sulfate Catabolic Process Cellular Carbohydrate Metabolic Process Response To Cortisone Response To Thyroglobulin Triiodothyronine
Pathways		Zinc efflux and compartmentalization by the SLC30 family	Glycosphingolipid metabolism Keratan sulfate degradation HS-GAG degradation MPS IV - Morquio syndrome B Sialic acid metabolism Defective NEU1 causes sialidosis Neutrophil degranulation
Drugs			Lactose
Diseases
GWAS			Allergic disease (asthma, hay fever or eczema) ( 29083406) Aspartate aminotransferase levels ( 33547301) Asthma ( 31361310 31959851 30929738 34103634 32296059 31619474) Asthma (adult onset) ( 30929738) Asthma (childhood onset) ( 31036433 30929738) Atopic dermatitis ( 23042114) Celiac disease ( 22057235) Eosinophil counts ( 29403010 32888494 27863252) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 32888494 27863252) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Hepatocellular carcinoma ( 21105107) Medication use (adrenergics, inhalants) ( 31015401) Medication use (glucocorticoids) ( 31015401) Neutrophil percentage of granulocytes ( 27863252) Sum eosinophil basophil counts ( 27863252)
Interacting Genes		66 interacting genes: ABHD16A ADAM33 AQP2 AQP6 ATP13A1 C5orf46 CCL4 CCL4L2 CD40 CD52 CD79A CD99L2 CPLX4 CREB3 CTSA CYB561D2 EBAG9 EMP3 EVI2B F11R FAM174A FDPS FFAR2 FXYD3 FXYD6 GALNT15 GJA5 GJB2 GJB5 GLB1 GOLT1A GPR161 GPR42 GPRC5D HGFAC KASH5 KCNN4 LMNA LTA LYVE1 MS4A13 NDUFAF1 NRM OPRM1 PCNX2 PLPPR1 PVR SEC22A SELL SERPING1 SLC10A6 SLC16A2 SLC18A1 SLC38A7 SLC39A2 SLC7A1 SLC7A8 TAS2R5 TM4SF18 TMEM107 TMEM52B TMEM60 TMEM86A TNFRSF12A TRARG1 YIPF2	12 interacting genes: CSNK2B CTSA DNAJB1 FOS GOLM1 NEU1 OGT PLK1 SLC10A6 SLC30A2 SLC7A1 TK1
Entrez ID		7780	2720
HPRD ID		18057	01975
Ensembl ID		ENSG00000158014	ENSG00000170266
Uniprot IDs		Q9BRI3	B7Z6Q5 P16278
PDB IDs			3THC 3THD 3WEZ 3WF0 3WF1 3WF2 3WF3 3WF4
Enriched GO Terms of Interacting Partners?
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