SLC30A2 and F11R

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		SLC30A2	F11R
Description		solute carrier family 30 member 2	F11 receptor
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Lysosomal Membrane Late Endosome Plasma Membrane Integral Component Of Membrane Intracellular Membrane-bounded Organelle	Plasma Membrane Cell-cell Junction Bicellular Tight Junction Integral Component Of Membrane Cell Junction Cytoplasmic Vesicle Protein-containing Complex Slit Diaphragm Extracellular Exosome Tight Junction
	Molecular Function	Zinc Ion Transmembrane Transporter Activity Protein Binding Identical Protein Binding	Virus Receptor Activity Integrin Binding Protein Binding PDZ Domain Binding Protein Homodimerization Activity Cadherin Binding
	Biological Process	Response To Zinc Ion Regulation Of Sequestering Of Zinc Ion Positive Regulation Of Sequestering Of Zinc Ion Zinc Ion Transmembrane Transport	Regulation Of Cytokine Production Inflammatory Response Leukocyte Cell-cell Adhesion Regulation Of Cell Shape Response To Radiation Actomyosin Structure Organization Regulation Of Actin Cytoskeleton Organization Negative Regulation Of GTPase Activity Positive Regulation Of Rho Protein Signal Transduction Maintenance Of Blood-brain Barrier Memory T Cell Extravasation Positive Regulation Of GTPase Activity Positive Regulation Of Blood Pressure Viral Entry Into Host Cell Intestinal Absorption Regulation Of Cytoskeleton Organization Negative Regulation Of Stress Fiber Assembly Cellular Response To Mechanical Stimulus Protein Localization To Plasma Membrane Establishment Of Endothelial Intestinal Barrier Regulation Of Membrane Permeability Cell-cell Adhesion Positive Regulation Of Platelet Aggregation Protein Localization To Bicellular Tight Junction Positive Regulation Of Establishment Of Endothelial Barrier Regulation Of Actin Cytoskeleton Reorganization Regulation Of Bicellular Tight Junction Assembly
Pathways		Zinc efflux and compartmentalization by the SLC30 family	Cell surface interactions at the vascular wall Integrin cell surface interactions TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) Tight junction interactions
Drugs
Diseases
GWAS			Inflammatory bowel disease ( 23128233) Night sleep phenotypes ( 27126917)
Interacting Genes		66 interacting genes: ABHD16A ADAM33 AQP2 AQP6 ATP13A1 C5orf46 CCL4 CCL4L2 CD40 CD52 CD79A CD99L2 CPLX4 CREB3 CTSA CYB561D2 EBAG9 EMP3 EVI2B F11R FAM174A FDPS FFAR2 FXYD3 FXYD6 GALNT15 GJA5 GJB2 GJB5 GLB1 GOLT1A GPR161 GPR42 GPRC5D HGFAC KASH5 KCNN4 LMNA LTA LYVE1 MS4A13 NDUFAF1 NRM OPRM1 PCNX2 PLPPR1 PVR SEC22A SELL SERPING1 SLC10A6 SLC16A2 SLC18A1 SLC38A7 SLC39A2 SLC7A1 SLC7A8 TAS2R5 TM4SF18 TMEM107 TMEM52B TMEM60 TMEM86A TNFRSF12A TRARG1 YIPF2	31 interacting genes: AFDN ASIP BDNF CAMLG CASK CGN CSNK2A1 EVL F2RL2 ITGAL JAGN1 MARCHF2 MMP14 MPDZ MYADM PARD3 PEX19 PGAP2 PICK1 PRKCA PTPRB RABAC1 SGTA SLC30A2 SLC35A1 SNAP47 STRIT1 TJP1 TMEM100 TMEM147 TMEM86B
Entrez ID		7780	50848
HPRD ID		18057	12038
Ensembl ID		ENSG00000158014	ENSG00000158769
Uniprot IDs		Q9BRI3	Q6FIB4 Q9Y624
PDB IDs			1NBQ 3EOY 3TSZ 4ODB
Enriched GO Terms of Interacting Partners?
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