PKN2 and PLCG1

  • Number of citations of the paper that reports this interaction (PubMedID 8910519)
  • 45
  • Data Source:
  • HPRD (in vitro)

PKN2

PLCG1

Description protein kinase N2 phospholipase C gamma 1
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Age at first sexual intercourse ( 34211149)
  • Alanine aminotransferase levels ( 33547301 34315874)
  • Aspartate aminotransferase levels ( 33547301 34315874)
  • Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143)
  • Coronary artery disease ( 29212778)
  • Diastolic blood pressure ( 27841878)
  • General risk tolerance (MTAG) ( 30643258)
  • Heel bone mineral density ( 30598549 28869591)
  • Height ( 20881960 25282103 31562340)
  • Intraocular pressure ( 29617998)
  • Liver enzyme levels (alanine transaminase) ( 33972514)
  • Liver enzyme levels (gamma-glutamyl transferase) ( 33972514 22001757)
  • Narcolepsy ( 23459209)
  • Neonatal total 25-hydroxyvitamin D levels (maternal genetic effect) ( 32047095)
  • Paclitaxel disposition in epithelial ovarian cancer ( 29367611)
  • Periodontal microbiota ( 22699663)
  • Photic sneeze reflex ( 27182965)
  • Pulse pressure ( 27841878)
  • Red blood cell count ( 32888494)
  • Refractive error ( 32231278)
  • Response to fenofibrate (LDL cholesterol levels) ( 27002377)
  • Rosacea symptom severity ( 29771307)
  • Serum protein levels (sST2) ( 23999434)
  • Subjective response to placebo treatment in childhood asthma (change in cough/wheeze) ( 31557306)
  • Systolic blood pressure ( 30224653 27841878)
  • Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993)
  • Vertical cup-disc ratio (multi-trait analysis) ( 31959993)
  • Waist circumference adjusted for body mass index ( 34021172)
  • White matter hyperintensity volume ( 33293549)
  • White matter hyperintensity volume (adjusted for hypertension) ( 33293549)
Interacting Genes 19 interacting genes: AKT1 CASP3 CCDC136 CHGB EEF1A1 EIF3G FAM193B HDAC5 MAP3K2 MYO9B NCK1 NCK2 NEDD4 PDPK1 PLCG1 PTBP2 PTPN13 RHOA SUMO2 111 interacting genes: ABL1 AGAP2 AGTR1 AKT1 ALK AR ARHGAP32 ARHGEF5 AXL BAG3 BCR BLNK BTK CBL CD22 CD28 CTSS DAB1 DAPP1 DDR1 DGKZ DNM1 DOK1 EEF1A1 EGFR EPHB2 EPOR ERBB2 ERBB3 ERBB4 FGFR1 FGFR2 FGFR4 FLT1 FYN GAB1 GAB2 GHR GIT1 GRAP GRB2 GRIN1 GRIN2A GRIN2B GSN GTF2H1 HCK INPP5D INSR IRS2 ITK KDR KHDRBS1 KIT LAT LAT2 LCK LCP2 LIFR LYN MAPT MET MST1R NCAM1 NCK1 NPM1 NTRK1 NTRK2 NTRK3 PAK1 PDGFRA PDGFRB PECAM1 PICALM PITPNA PKN2 PLD2 PRKD1 PRMT8 PTK2 PTPN11 PTPRJ RACK1 RET RHOA RHOU SELE SH2D2A SH3BP2 SHB SHC1 SNAP91 SOCS7 SOS1 SOS2 SRC SYK SYN1 SYNCRIP TEC TNK1 TRIM14 TRPC3 TRPM7 TUB USO1 VAV1 VAV3 VIL1 WAS ZAP70
Entrez ID 5586 5335
HPRD ID 03972 01398
Ensembl ID ENSG00000065243 ENSG00000124181
Uniprot IDs Q16513 P19174 Q4LE43 Q9UFY1
PDB IDs 4CRS 4RRV 6CCY 6GBE 1HSQ 2HSP 4EY0 4FBN
Enriched GO Terms of Interacting Partners?
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