Description |
phospholipase C gamma 1 |
inositol polyphosphate-5-phosphatase D |
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GO Annotations |
Cellular Component |
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Molecular Function |
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- Phosphatidylinositol-4,5-bisphosphate 5-phosphatase Activity
- Inositol-polyphosphate 5-phosphatase Activity
- Protein Binding
- Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase Activity
- SH3 Domain Binding
- Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase Activity
- Inositol-1,4,5-trisphosphate 5-phosphatase Activity
- Inositol-1,3,4,5-tetrakisphosphate 5-phosphatase Activity
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Biological Process |
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Pathways |
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Drugs |
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Diseases |
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GWAS |
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- Allergic disease (asthma, hay fever or eczema) ( 29083406)
- Alzheimer's disease (late onset) ( 30617256 24162737)
- Alzheimer's disease or family history of Alzheimer's disease ( 30617256)
- Contrast sensitivity ( 24152035)
- Crohn's disease ( 22412388 23128233)
- Eosinophil counts ( 32888494 27863252)
- Eosinophil percentage of granulocytes ( 27863252)
- Eosinophil percentage of white cells ( 32888494 27863252)
- Family history of Alzheimer's disease ( 30617256)
- High light scatter reticulocyte count ( 32888494)
- High light scatter reticulocyte percentage of red cells ( 32888494)
- Immature fraction of reticulocytes ( 32888494)
- Monocyte count ( 32888494)
- Neutrophil count ( 32888494)
- Neutrophil percentage of granulocytes ( 27863252)
- Perceived unattractiveness to mosquitoes ( 28199695)
- Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1) ( 26503814)
- Serum alkaline phosphatase levels ( 33547301)
- Sum eosinophil basophil counts ( 27863252)
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Interacting Genes |
111 interacting genes:
ABL1
AGAP2
AGTR1
AKT1
ALK
AR
ARHGAP32
ARHGEF5
AXL
BAG3
BCR
BLNK
BTK
CBL
CD22
CD28
CTSS
DAB1
DAPP1
DDR1
DGKZ
DNM1
DOK1
EEF1A1
EGFR
EPHB2
EPOR
ERBB2
ERBB3
ERBB4
FGFR1
FGFR2
FGFR4
FLT1
FYN
GAB1
GAB2
GHR
GIT1
GRAP
GRB2
GRIN1
GRIN2A
GRIN2B
GSN
GTF2H1
HCK
INPP5D
INSR
IRS2
ITK
KDR
KHDRBS1
KIT
LAT
LAT2
LCK
LCP2
LIFR
LYN
MAPT
MET
MST1R
NCAM1
NCK1
NPM1
NTRK1
NTRK2
NTRK3
PAK1
PDGFRA
PDGFRB
PECAM1
PICALM
PITPNA
PKN2
PLD2
PRKD1
PRMT8
PTK2
PTPN11
PTPRJ
RACK1
RET
RHOA
RHOU
SELE
SH2D2A
SH3BP2
SHB
SHC1
SNAP91
SOCS7
SOS1
SOS2
SRC
SYK
SYN1
SYNCRIP
TEC
TNK1
TRIM14
TRPC3
TRPM7
TUB
USO1
VAV1
VAV3
VIL1
WAS
ZAP70
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46 interacting genes:
ARAP1
CD22
CD300LF
CRKL
CSF1R
CSF3R
CYSRT1
DAB1
DAB2
DOK1
DOK2
DOK3
EPOR
FCGR1B
FCGR2B
FGR
FLT3
GAB1
GAB2
GRB2
HCK
IL4R
JAK1
JAK3
KHDRBS3
KIT
KRT31
KRT40
KRTAP1-3
KRTAP10-3
KRTAP10-7
KRTAP10-9
KRTAP6-3
LILRB4
LYN
MET
NOTCH2NLA
PAX6
PECAM1
PLCG1
PTPN11
SH3KBP1
SHC1
SLAMF1
XIAP
ZDHHC17
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Entrez ID |
5335 |
3635 |
HPRD ID |
01398 |
09033 |
Ensembl ID |
ENSG00000124181
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ENSG00000168918
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Uniprot IDs |
P19174
Q4LE43
Q9UFY1
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Q92835
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PDB IDs |
1HSQ
2HSP
4EY0
4FBN
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2YSX
5RW2
5RW3
5RW4
5RW5
5RW6
5RW7
5RW8
5RW9
5RWA
5RWB
5RWC
5RWD
5RWE
5RWF
5RWG
5RWH
5RWI
5RWJ
5RWK
5RWL
5RWM
5RWN
5RWO
5RWP
5RWQ
5RWR
5RWS
5RWT
5RWU
5RWV
5RWW
5RWX
5RWY
5RWZ
5RX0
5RX1
5RX2
5RX3
5RX4
5RX5
5RX6
5RX7
5RX8
5RX9
5RXA
5RXB
5RXC
5RXD
5RXE
5RXF
5RXG
5RXH
5RXI
5RXJ
5RXK
5RXL
5RXM
5RXO
5RXP
5RXQ
5RXR
5RXS
5RXT
5RXU
5RXV
5RXW
5RXX
5RXY
5RXZ
5RY0
5RY1
5RY2
5RY3
5RY4
5RY5
5RY6
5RY7
5RY8
5RY9
5RYA
5RYB
5RYC
5RYD
5RYE
5RYF
5RYG
5RYH
5RYI
5RYJ
5RYK
5RYL
6IBD
6XY7
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Enriched GO Terms of Interacting Partners? |
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Tagcloud ? |
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Tagcloud (Difference) ? |
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Tagcloud (Intersection) ? |
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