PKN2 and FAM193B

  • Number of citations of the paper that reports this interaction (PubMedID 21900206)
  • 136
  • Data Source:
  • BioGRID (two hybrid)

PKN2

FAM193B

Description protein kinase N2 family with sequence similarity 193 member B
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Age at first sexual intercourse ( 34211149)
  • Alanine aminotransferase levels ( 33547301 34315874)
  • Aspartate aminotransferase levels ( 33547301 34315874)
  • Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143)
  • Coronary artery disease ( 29212778)
  • Diastolic blood pressure ( 27841878)
  • General risk tolerance (MTAG) ( 30643258)
  • Heel bone mineral density ( 30598549 28869591)
  • Height ( 20881960 25282103 31562340)
  • Intraocular pressure ( 29617998)
  • Liver enzyme levels (alanine transaminase) ( 33972514)
  • Liver enzyme levels (gamma-glutamyl transferase) ( 33972514 22001757)
  • Narcolepsy ( 23459209)
  • Neonatal total 25-hydroxyvitamin D levels (maternal genetic effect) ( 32047095)
  • Paclitaxel disposition in epithelial ovarian cancer ( 29367611)
  • Periodontal microbiota ( 22699663)
  • Photic sneeze reflex ( 27182965)
  • Pulse pressure ( 27841878)
  • Red blood cell count ( 32888494)
  • Refractive error ( 32231278)
  • Response to fenofibrate (LDL cholesterol levels) ( 27002377)
  • Rosacea symptom severity ( 29771307)
  • Serum protein levels (sST2) ( 23999434)
  • Subjective response to placebo treatment in childhood asthma (change in cough/wheeze) ( 31557306)
  • Systolic blood pressure ( 30224653 27841878)
  • Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993)
  • Vertical cup-disc ratio (multi-trait analysis) ( 31959993)
  • Waist circumference adjusted for body mass index ( 34021172)
  • White matter hyperintensity volume ( 33293549)
  • White matter hyperintensity volume (adjusted for hypertension) ( 33293549)
  • Waist-to-hip ratio adjusted for BMI ( 26426971)
  • Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971)
  • Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes 19 interacting genes: AKT1 CASP3 CCDC136 CHGB EEF1A1 EIF3G FAM193B HDAC5 MAP3K2 MYO9B NCK1 NCK2 NEDD4 PDPK1 PLCG1 PTBP2 PTPN13 RHOA SUMO2 12 interacting genes: ATXN1 CDC25A CNOT11 GOLGA2 GSK3A GSK3B LDOC1 MAPK8 PKN2 SPANXN2 TRIM23 TRIM27
Entrez ID 5586 54540
HPRD ID 03972 07671
Ensembl ID ENSG00000065243 ENSG00000146067
Uniprot IDs Q16513 Q6IPW0 Q96PV7
PDB IDs 4CRS 4RRV 6CCY 6GBE
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?