PLS3 and ASGR1

		PLS3	ASGR1
Description		plastin 3	asialoglycoprotein receptor 1
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GO Annotations	Cellular Component	Cytoplasm Cytosol Actin Filament Plasma Membrane Actin Filament Bundle	Extracellular Region Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	Calcium Ion Binding Actin Filament Binding	Asialoglycoprotein Receptor Activity Protein Binding Carbohydrate Binding Identical Protein Binding Metal Ion Binding
	Biological Process	Actin Filament Bundle Assembly Actin Filament Network Formation Bone Development	Receptor-mediated Endocytosis Cellular Response To Extracellular Stimulus
Pathways			Asparagine N-linked glycosylation
Drugs
Diseases
GWAS		Gestational age at birth (maternal effect) ( 28877031) Mean platelet volume ( 32888494) Platelet count ( 32888494) Platelet distribution width ( 32888494) Preterm birth (maternal effect) ( 28877031)	Apolipoprotein B levels ( 32203549) Iron status biomarkers (ferritin levels) ( 33536631) LDL cholesterol levels ( 32203549) Liver enzyme levels (alkaline phosphatase) ( 33972514 22001757) Low density lipoprotein cholesterol levels ( 32154731 33339817) Medication use (HMG CoA reductase inhibitors) ( 31015401) Serum alkaline phosphatase levels ( 33547301 31666285 29403010 33339817) Total cholesterol levels ( 33339817)
Interacting Genes		17 interacting genes: ACRV1 APP ASGR1 ATXN2 CUL4B CXCR5 FRYL LRCH2 NRSN1 OGT PTPN5 TGIF2 TRPC5 TSPAN32 WFDC2 ZBTB33 ZNF195	44 interacting genes: AHNAK2 AMIGO1 APH1A APP ASGR2 ATP1B4 BLCAP CERS2 CLDN7 CLEC4G CPLX4 CREB3L1 CYB5R3 DHFR ERGIC3 FAM209A FCGR1A FNDC9 GPX8 HIBADH HIVEP1 HSP90AA1 HSP90B1 IGFBP5 KIR2DL3 LAMTOR5 LEUTX LMNA MCEMP1 NEMP1 NLK PDZK1IP1 PLS3 RBBP6 RNF19B SAR1A SLC10A1 SLC35C2 SPAG4 SUSD3 TG TMX2 VKORC1 VSIR
Entrez ID		5358	432
HPRD ID		02133	00151
Ensembl ID		ENSG00000102024	ENSG00000141505
Uniprot IDs		B4DPW9 P13797	P07306 Q6FGQ5
PDB IDs		1AOA 1WJO	1DV8 5JPV 5JQ1 6YAU
Enriched GO Terms of Interacting Partners?
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