ASGR1 and NEMP1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		ASGR1	NEMP1
Description		asialoglycoprotein receptor 1	nuclear envelope integral membrane protein 1
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Plasma Membrane Integral Component Of Plasma Membrane	Nuclear Envelope Nuclear Inner Membrane Integral Component Of Membrane
	Molecular Function	Asialoglycoprotein Receptor Activity Protein Binding Carbohydrate Binding Identical Protein Binding Metal Ion Binding	Molecular_function
	Biological Process	Receptor-mediated Endocytosis Cellular Response To Extracellular Stimulus	Nuclear Membrane Organization
Pathways		Asparagine N-linked glycosylation
Drugs
Diseases
GWAS		Apolipoprotein B levels ( 32203549) Iron status biomarkers (ferritin levels) ( 33536631) LDL cholesterol levels ( 32203549) Liver enzyme levels (alkaline phosphatase) ( 33972514 22001757) Low density lipoprotein cholesterol levels ( 32154731 33339817) Medication use (HMG CoA reductase inhibitors) ( 31015401) Serum alkaline phosphatase levels ( 33547301 31666285 29403010 33339817) Total cholesterol levels ( 33339817)	Asthma ( 31959851)
Interacting Genes		44 interacting genes: AHNAK2 AMIGO1 APH1A APP ASGR2 ATP1B4 BLCAP CERS2 CLDN7 CLEC4G CPLX4 CREB3L1 CYB5R3 DHFR ERGIC3 FAM209A FCGR1A FNDC9 GPX8 HIBADH HIVEP1 HSP90AA1 HSP90B1 IGFBP5 KIR2DL3 LAMTOR5 LEUTX LMNA MCEMP1 NEMP1 NLK PDZK1IP1 PLS3 RBBP6 RNF19B SAR1A SLC10A1 SLC35C2 SPAG4 SUSD3 TG TMX2 VKORC1 VSIR	32 interacting genes: ADIPOQ AQP10 ASGR1 BRICD5 C3orf52 C5 CD81 CLEC7A CLRN2 CNIH3 COL4A5 CXCL16 CXCL9 FAXDC2 GPR108 GUCA2A INHBE INSIG2 PNLIPRP1 RTP2 SCARF1 SERP2 STX12 TMEM14A TMEM229B TMEM42 TMEM86B TMEM97 TMUB2 TSPAN33 UPK1B VAMP3
Entrez ID		432	23306
HPRD ID		00151	13793
Ensembl ID		ENSG00000141505	ENSG00000166881
Uniprot IDs		P07306 Q6FGQ5	O14524
PDB IDs		1DV8 5JPV 5JQ1 6YAU
Enriched GO Terms of Interacting Partners?
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