ASGR1 and LEUTX

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		ASGR1	LEUTX
Description		asialoglycoprotein receptor 1	leucine twenty homeobox
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Plasma Membrane Integral Component Of Plasma Membrane	Chromatin Nucleus
	Molecular Function	Asialoglycoprotein Receptor Activity Protein Binding Carbohydrate Binding Identical Protein Binding Metal Ion Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding
	Biological Process	Receptor-mediated Endocytosis Cellular Response To Extracellular Stimulus	Regulation Of Transcription By RNA Polymerase II
Pathways		Asparagine N-linked glycosylation
Drugs
Diseases
GWAS		Apolipoprotein B levels ( 32203549) Iron status biomarkers (ferritin levels) ( 33536631) LDL cholesterol levels ( 32203549) Liver enzyme levels (alkaline phosphatase) ( 33972514 22001757) Low density lipoprotein cholesterol levels ( 32154731 33339817) Medication use (HMG CoA reductase inhibitors) ( 31015401) Serum alkaline phosphatase levels ( 33547301 31666285 29403010 33339817) Total cholesterol levels ( 33339817)	Macular thickness ( 30535121)
Interacting Genes		44 interacting genes: AHNAK2 AMIGO1 APH1A APP ASGR2 ATP1B4 BLCAP CERS2 CLDN7 CLEC4G CPLX4 CREB3L1 CYB5R3 DHFR ERGIC3 FAM209A FCGR1A FNDC9 GPX8 HIBADH HIVEP1 HSP90AA1 HSP90B1 IGFBP5 KIR2DL3 LAMTOR5 LEUTX LMNA MCEMP1 NEMP1 NLK PDZK1IP1 PLS3 RBBP6 RNF19B SAR1A SLC10A1 SLC35C2 SPAG4 SUSD3 TG TMX2 VKORC1 VSIR	46 interacting genes: AGPAT4 AIG1 AQP2 AQP3 ASGR1 C1GALT1 C1QL4 C3orf52 CDS2 CMTM3 CMTM5 CNIH1 CNIH3 CXCL9 EMP3 ENTPD3 FAM24B FZD7 GOSR2 KIR2DL3 LAT MRPL57 MS4A1 NAPB NDRG4 OLFM4 PLP1 PNLIPRP1 PRB1 SLC13A3 SLC30A8 SLC41A2 STATH TF TMEM128 TMEM147 TMEM187 TMEM254 TMEM60 TMEM97 TSPO TTPA UNC93B1 VAMP4 ZFPL1 ZNF646
Entrez ID		432	342900
HPRD ID		00151
Ensembl ID		ENSG00000141505	ENSG00000213921
Uniprot IDs		P07306 Q6FGQ5	A8MZ59
PDB IDs		1DV8 5JPV 5JQ1 6YAU
Enriched GO Terms of Interacting Partners?
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